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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 204451 - 204460 of 207725 results
  1. TOPIC 421: BUILDING THE WORLD'S FIRST CLINICAL OXYGEN IMAGER FOR EFFICIENT CANCER TREATMENT

    SBC: O2M TECHNOLOGIES LLC            Topic: 421

    2019 Nobel prize in medicine for the discovery of oxygen signaling pathways highlights the importance of oxygenation as a physiologic parameter. Oxygenation plays a key role in cancer development and may affect its aggressiveness. Tumors have a highly heterogeneous oxygen environment which affects the outcome of chemo- and radiation treatment. Hypoxia, or low oxygenation, is an obstacle to success ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 421: BIOMIMETIC OPTICAL PHANTOMS FOR ADVANCING DEVELOPMENT OF FLUORESCENCE GUIDED SURGERY

    SBC: Quel Imaging LLC            Topic: 421

    Fluorescence guidance for surgical resection of cancerous tissue is a rapidly growing field, providing real time guidance with molecular or vascular flow specificity. System calibration and performance validation is generally performed on an ad hoc basis and largely driven by manufacturers choices to minimize up-front cost, yet is entirely necessary as more manufacturers are approved. QUEL Imaging ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  3. MOONSHOT- TOPIC 423- AN INTEGRATED MULTI-LEVEL DECISION SUPPORT PLATFORM TO ADDRESS PATIENT-CENTERED AND EVIDENCE-BASED SOCIAL DETERMINANTS OF HEALT

    SBC: PISTEVO DECISION LLC            Topic: 423

    A strong body of evidence demonstrates that addressing Social Determinants of Health (SDH) within healthcare systems advances cancer treatment adherence and outcomes. Preventable cancer deaths continue to occur because of un-addressed SDH challenges across socioeconomic groups and races. Integrating SDH along with clinical information within operational CDS systems built into Electronic Health Rec ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  4. SBIR PHASE I- TOPIC 426- TOOLS AND TECHNOLOGIES FOR VISUALIZING MULTI-SCALE DATA

    SBC: QUANTITATIVE IMAGING SYSTEMS LLC            Topic: 426

    The Swift project will create an integrated interactive visualization software system for visual analysis of highly multiplex microscopy images of complex cancer samples from nanoscale molecular and architectural features up to single cell and tissue scales. To avoid spatial crowding on 2D displays and taking advantage of the human mind's cognitive coherence, a fully web-enabled Augmented Reality ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR TOPIC 417; PHASE I; FIRM FIXED PRICEDELIVERY: 06/14/2022PERIOD OF PERFORMANCE: 09/15/2021 TO 12/14/2022

    SBC: NEURALRAD LLC            Topic: 417

    It was estimated that ~170,000 patients diagnosed with Brain metastases (BMs) in United States each year and most patients have clinical manifestation of multiple BMs (mBMs). Stereotactic radiosurgery (SRS) has been used frequently for treating mBMs and demonstrated much less toxicity than conventional whole brain radiotherapy. Current SRS platform was designed for single-fraction treatment on lim ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. PHASE I SBIR CONTRACT- TOPIC 415- COMPACT AND RETROFITTABLE ELECTRONIC BRACHYTHERAPY SOURCE FOR CANCER RADIOTHERAPY.

    SBC: EUCLID BEAMLABS LLC            Topic: 415

    The use of electronic brachytherapy (EB) has grown rapidly over the past decade, and is gaining significant interest from the global medical community as an improved user-friendly technology. However, the present EB machines all use electron beams at energies of 100 kV or less to generate the X-ray photons, which limits their use to low dose-rate brachytherapy. In this proposal, Euclid Beamlabs fo ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 424- MYH 2.0: A DIGITAL EXPERIENCE TO IMPROVE SURVIVORSHIP AMONG AYA CANCER SURVIVORS

    SBC: Radiant Creative Group, LLC            Topic: 424

    Adolescent and Young Adult (AYA) cancer survivors are expected to assume primary responsibility for their healthcare when they reach adulthood. However, only a minority (lt18%) of adult childhood cancer survivors obtain risk-based follow-up care. Transition readiness is a critical precursor to adult self-management of care, and adult self-management improves health status and reduces healthcare ut ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 425- AUTOMATED MOTION EXTRACTION AND ANALYSIS TO QUANTIFY PATIENT PERFORMANCE STATUS

    SBC: CANSERA INC            Topic: 425

    The Karnofsky score (1948) and the Eastern Cooperative Group ECOG PS (1982) are the standard for patient PS assessment and used as a key determinant for entry into a clinical trial and the initiation or continuation of any interventional therapy. Cansera has demonstrated using image analysis of footage from RGB-D cameras to quantify PS as a predictive biomarker in cancer care. RGB-D cameras captur ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR PHASE I- TOPIC 426- TOOLS AND TECHNOLOGIES FOR VISUALIZING MULTI-SCALE DATA

    SBC: KITWARE INC            Topic: 426

    This work enables the sharing of complex information in the form of an interactive data atlas. The atlas enables researchers to organize large, heterogeneous data into a form that can be easily viewed, explored, analyzed, and disseminated through a web browser, even when the data is distributed across multiple computers and cloud resources. In particular, the atlas is designed to represent biologi ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 388: IN VITRO DIAGNOSTIC FOR THE LIVER FLUKES OPISTHORCHIS VIVERRINI AND CLONORCHIS SINENSI

    SBC: KEPHERA DIAGNOSTICS LLC            Topic: 388

    This proposal addresses the significant public health threat posed by the liver flukes Clonorchis sinensis and Opisthorchis viverrini in at-risk human populations including personnel stationed in Southeast Asia for military or government service in previous decades. Infection with the two liver flukes is associated with a greater risk for cholangiocarcinoma, a highly lethal cancer of the bile duct ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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