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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 204491 - 204500 of 207714 results
  1. TOPIC 433: A FEDERATED DATA PLATFORM FOR DEVELOPING UNBIASED BREAST IMAGING AI

    SBC: FLYWHEEL EXCHANGE, LLC            Topic: 433

    This SBIR project aims to implement a federated data platform focused on a data system to enable mammography data to be published into a federated catalog from which collaborators can execute federated analyses. It will enable hospitals and other clinical entities to make their data available for training and validation of artificial intelligence applications. The data federation will include a ra ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  2. SBIR PHASE I TOPIC 431, INTEGRATED CELL CULTURE CHAMBER AND FLOW GUIDE FOR POC, WALK-AWAY OPERATION FOR AUTOLOGOUS T CELL MANUFACTURING

    SBC: SPATIAL SURGICAL LLC            Topic: 431

    Surgical resection is required in approximately 80% of cancers presenting solid tumors. Despite advancing technologies, countries categorized as LMICs show an increase in incidences of various cancers. The lack of preventative screenings, and the associated infrastructure, make both identification and screening of cancers difficult. The long-term objective of this work is to build a benchtop CO2 l ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. PROJECT TITLE: AUTOMATIC TREATMENT PLANNING OF CERVICAL CANCER HIGH-DOSE RATE BRACHYTHERAPY FOR LOW-RESOURCE SETTINGS

    SBC: VELOXAI LLC            Topic: 431

    Cervical cancer is a major disease globally and 85% of the cancer burden occurs in low- and middle-income countries (LMICs). Standard of care is external-beam radiotherapy with high dose-rate brachytherapy (HDRBT). Adding brachytherapy to the treatment course improves overall survival by 12% and reduces local recurrence. HDRBT treatment planning is a complex process. Brachytherapy in low-resource ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Rapid at-home Detection for Serologic Status of Hepatitis C Virus (HCV) Infection

    SBC: QOOLABS INC            Topic: 441

    Hepatitis C Virus (HCV) infection is a worldwide health concern, affecting about 3% of the world’s population. Over 2 million people in the United States have a current HCV infection, however, nearly half of them are not aware of their infection. HCV-related end stage liver disease is the leading reason for liver transplantation in the USA. Because symptoms are generally absent in individuals wi ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 430: A NEW SMALL MOLECULE SENOTHERAPEUTIC FOR THE CHEMOPREVENTION OF THERAPY-RELATED COGNITIVE AGING

    SBC: TRITERPENOID THERAPEUTICS INC            Topic: 430

    Cognitive impairment is a cause of significant morbidity and diminished quality of life for cancer survivors and particularly for survivors of childhood cancer. There is now substantial evidence supporting the role of the pro-inflammatory, senescence-associated secretory phenotype (SASP) as a major contributor to cognitive aging and other age-related diseases. Microglial senescence has profound co ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR TOPIC 431- MOBILE ORAL-CANCER SCREENING AND TREATMENT (MOST) SYSTEM FOR LOW-RESOURCE SETTINGS

    SBC: LIGHT RESEARCH INC.            Topic: 431

    Oral and oropharyngeal squamous cell carcinoma (OSCC) together rank as the sixth most common cancer worldwide, it is the most common cancer in some low- and middle- income countries (LMICs). The poor survival rate in LMICs and rural regions in developed countries is mainly due to late diagnosis and the resultant progression of disease to an advanced stage at diagnosis. Motivated by the successes i ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. AN INTERPRETABLE PHYSICIAN-IN-THE-LO

    SBC: MRIMATH LLC            Topic: 402

    MRIMath technology uses Artificial Intelligence (AI) to deliver pixel-level contouring of brain tumors from surrounding healthy tissue to shorten the time it takes to plan radiation treatment, reduce variability among oncologists, and boost patient outcomes. Tumor delineation and quantification remains the weakest link in the search for accuracy in radiotherapy. Inaccuracy and variation in definin ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. PROJECT TITLE: COLLABORATE IN THE CLOUD TO ENABLE PRECISION ONCOLOGY

    SBC: NAVIPOINT GENOMICS LLC            Topic: 407

    Precision oncology offers great potential in improving cancer-related diagnosis and treatment. The Navipoint Platform provides state of the art tools, pipelines, and cloud-based resources, which will be extended and integrated with CRDC data and resources in order to enable “Collaborate in the Cloud” capabilities to help realize this promise. The product of this SBIR will be a production-grade ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. TOPIC 403: DEVELOPMENT OF SPATIAL MICROPURIFICATION TECHNOLOGY

    SBC: AVONEAUX MEDICAL INSTITUTE, LLC            Topic: 403

    The tumor microenvironment (TME) comprises a mixture of cell types, including tumor cells, cancer sub-clones, metaplasia, dysplasia, desmoplasia, reactive fibroblasts, and a complex immune response. Measuring the molecular status of each cellular component within the TME is important to understanding tumor initiation and progression as well as in determining the interplay between cancer and normal ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 405: INTRATUMORAL BIOSENSING FOR IN VIVO PHARMACOTYPING

    SBC: LODESTONE BIOMEDICAL LLC            Topic: 405

    This project addresses the problem that several rounds of varied immunotherapy treatments over an extended period are often needed to find one that is effective in treating tumors in a particular patient. The proposed solution is an Immunotherapy Response Indication System (IRIS) to monitor treatment response directly in a patient’s own tumor while testing sub therapeutic doses of multiple candi ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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