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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

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Displaying 204641 - 204650 of 207712 results
  1. IMI-TECH CORPORATION PROPOSES TO DETERMINE THE FEASIBILITY OF MEETING THE NAVY'S NEED FOR A POURED-IN-PLACE, LIGHTWEIGHT FLOTATION FOAM THAT WILL NOT SUSTAIN COMBUSTION, DOES NOT RELEASE HAZARDOUS AMOUNTS OF TOXIC GASES WHEN EXPOSED TO FLAMES, AND HAS

    SBC: Imi-tech Corp            Topic: N/A

    IMI-TECH CORPORATION PROPOSES TO DETERMINE THE FEASIBILITY OF MEETING THE NAVY'S NEED FOR A POURED-IN-PLACE, LIGHTWEIGHT FLOTATION FOAM THAT WILL NOT SUSTAIN COMBUSTION, DOES NOT RELEASE HAZARDOUS AMOUNTS OF TOXIC GASES WHEN EXPOSED TO FLAMES, AND HAS LOW WATER ABSORPTION. THE TECHNOLOGY TO MEET THIS REQUIREMENT, WITHOUT THE USE OF TOXIC GAS-PRODUCING FLAME RETARDANTS, EXISTS AT IMI-TECH TODAY. TH ...

    SBIR Phase I 1985 Department of DefenseNavy
  2. FEASIBILITY STUDIES FOR DEVELOPING A NOVEL CLINICAL DEVICE ARE PROPOSED.

    SBC: Immunicon Corporation            Topic: N/A

    FEASIBILITY STUDIES FOR DEVELOPING A NOVEL CLINICAL DEVICE ARE PROPOSED. THIS DEVICE WHICH WOULD USE IMMUNOLOGICAL AND COMPLEMENT REAGENTS IN CONJUNCTION WITH FILTRATION AND/OR ONE OR MORE MAGNETIC RETRIEVAL SYSTEMS TO PRODUCE A NEW SEPARATION AND COLLECTION TECHNOLOGY COULD RESULT IN TOTALLY NEW MODALITIES OF TREATMENT FOR NUMEROUS DISEASE STATES WHICH CURRENTLY ARE CLASSIFIED AS UNTREATABLE. THI ...

    SBIR Phase I 1985 Department of Health and Human Services
  3. THE OBJECT OF THIS PROJECT IS TO PRODUCE A KIT THAT UTILIZES ANTI-CSAP MONOCLONAL ANTIBODIES (MABS) FOR CLINICAL RADIOIMMUNODETECTION (RAID) OF COLORECTAL AND PANCREATIC CANCERS.

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    THE OBJECT OF THIS PROJECT IS TO PRODUCE A KIT THAT UTILIZES ANTI-CSAP MONOCLONAL ANTIBODIES (MABS) FOR CLINICAL RADIOIMMUNODETECTION (RAID) OF COLORECTAL AND PANCREATIC CANCERS. PHASE I WILL BE DEVOTED TO SELECTION OF HYBRIDOMAS WITH SPECIFICITY TO CSAP, AND MABS THAT ARE SUITABLE FOR IMAGING. IT WILL BE ACHIEVED BY INVESTIGATING THEIR IN VIVO DISTRIBUTION IN TUMOR AND NONTUMOR TISSUES USING AN A ...

    SBIR Phase I 1985 Department of Health and Human Services
  4. THIS PROJECT WILL EVALUATE ANTIBODY-MEDIATED, POLYMER-BOUND YTTRIUM-90 AS A CANCER THERAPY AGENT.

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    THIS PROJECT WILL EVALUATE ANTIBODY-MEDIATED, POLYMER-BOUND YTTRIUM-90 AS A CANCER THERAPY AGENT. ANTIBODIES WILL BE COUPLED THROUGH ONE COVALENT BOND TO A SMALL POLYLYSINE UNIT. THE LATTER WILL CARRY, VIA A BIFUNCTIONAL COUPLING AGENT, MOLECULES OF THE TRIVALENT METAL CHELATING SIDEROPHORE, DEFEROXAMINE. EACH DEFEROXAMINE WILL BE COMPLEXED WITH A SINGLE ATOM OF YTTRIUM-90, A HIGH ENERGY BETA-EMIT ...

    SBIR Phase I 1985 Department of Health and Human Services
  5. THIS PROJECT IS CONCERNED WITH THE DEVELOPMENT OF NONENZYMATIC REAGENTS FOR IMMUNOHISTOCHEMISTRY, WITH EMPHASIS ON ADAPTING THE NEW TECHNOLOGY TO THE EXPANDING FIELD OF IMMUNOHISTOCHEMICAL DIAGNOSIS OF CANCER.

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    THIS PROJECT IS CONCERNED WITH THE DEVELOPMENT OF NONENZYMATIC REAGENTS FOR IMMUNOHISTOCHEMISTRY, WITH EMPHASIS ON ADAPTING THE NEW TECHNOLOGY TO THE EXPANDING FIELD OF IMMUNOHISTOCHEMICAL DIAGNOSIS OF CANCER. PHASE I INVOLVES THE DEVELOPMENT OF THE FIRST FAMILY OF REAGENTS, NAMELY, PHENAZINE DERIVATIVES CONJUGATED TO ANTIBODIES AGAINST TUMOR-ASSOCIATED ANTIGENS, AND DETERMINATION OF STABILITY, IM ...

    SBIR Phase I 1985 Department of Health and Human Services
  6. MONOCLONAL ANTIBODY FOR THERAPY AND DIAGNOSIS

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services
  7. WE PROPOSE TO DEVELOP A STANDARDIZED KIT OF MONOCLONAL ANTIBODY (MOAB) CONJUGATED WITH A NOVEL BIOLOGICAL CATALYST TOXIN TO BE USED FOR THE EX VIVO ELIMINATION OF NEOPLASTIC CELLS FROM HUMAN AUTOLOGOUS BONE MARROW GRAFTS.

    SBC: Immunotechnology Of Indiana, I            Topic: N/A

    WE PROPOSE TO DEVELOP A STANDARDIZED KIT OF MONOCLONAL ANTIBODY (MOAB) CONJUGATED WITH A NOVEL BIOLOGICAL CATALYST TOXIN TO BE USED FOR THE EX VIVO ELIMINATION OF NEOPLASTIC CELLS FROM HUMAN AUTOLOGOUS BONE MARROW GRAFTS. THE TECHNICAL OBJECTIVES ARE TO PREPARE A TOXIN-CONJUGATED MURINE MOAB THAT WILL SPECIFICALLY BIND TO ANTIGEN POSITIVE NEOPLASTIC CELLS PRESENT IN AUTOLOGOUS BONE MARROW GRAFTS B ...

    SBIR Phase I 1985 Department of Health and Human Services
  8. A SERIES OF FUCOSYLATED GLYCOSPHINGOLIPIDS WITH THE ""X'' DETERMINANT (GAL 1 4FUC 1 3GLCNAC) HAVE BEEN SHOWN TO ACCUMULATE IN HUMAN COLONIC AND LIVER ADENOCARCINOMA AND ARE VIRTUALLY ABSENT IN NORMAL COLONIC MUCOSA AND NORMAL LIVER TISSUE.

    SBC: Imr+e Corpon            Topic: N/A

    A SERIES OF FUCOSYLATED GLYCOSPHINGOLIPIDS WITH THE ""X'' DETERMINANT (GAL 1 4FUC 1 3GLCNAC) HAVE BEEN SHOWN TO ACCUMULATE IN HUMAN COLONIC AND LIVER ADENOCARCINOMA AND ARE VIRTUALLY ABSENT IN NORMAL COLONIC MUCOSA AND NORMAL LIVER TISSUE. HOWEVER, SMALL QUANTITIES OF FUCOLIPIDS WITH THE ""X'' DETERMINANT (LEX) ARE DISTRIBUTED IN NORMAL TISSUES, SUCH AS GASTRIC EPITHELIA AND KIDNEY TUBULES. PRELIM ...

    SBIR Phase I 1985 Department of Health and Human Services
  9. EASIER TO CONJUGATE TO ANTIBODIES WITH HIGHER REPRODUCIBILITY.

    SBC: Imr+e Corpon            Topic: N/A

    EASIER TO CONJUGATE TO ANTIBODIES WITH HIGHER REPRODUCIBILITY.THE AIM OF THIS RESEARCH IS TO ISOLATE AND CHARACTERIZE ANTIGENS IN CIRCULATING IMMUNE COMPLEXES (CIC) FROM PATIENTS WITH ACQUIRED IMMUNODEFICIENCY SYNDROME AND KAPOSI'S SARCOMA (AIDS-KS) AND TO EXPLOIT THESE ANTIGENS FOR DEVELOPMENT OF NEW DIAGNOSTIC AND PROGNOSTIC REAGENTS. ELUATES FROM COLUMNS OF STAPHYLOCOCCUS AUREUSCOWAN I PROTEIN ...

    SBIR Phase I 1985 Department of Health and Human Services
  10. EFFICIENT, AND ECONOMICAL ALTERNATIVE ENERGY SUPPLY

    SBC: Incon Corp            Topic: N/A

    DECLINING ENERGY RESOURCES AND ENVIRONMENTAL PROBLEMS ASSOCIATED WITH THE PRODUCTION AND IMPORTATION OF FOSSIL FUELS AND THE PRODUCTION OF NUCLEAR ENERGY HAVE PRODUCED A NEED FOR RESEARCH & DEVELOPMENT OF SAFE, EFFICIENT, AND ECONOMICAL ENERGY ALTERNATIVES. SOLUTIONS MUST BE FOUND THAT CAN CONTRIBUTE A SIGNIFICANT PERCENTAGE OF THE U.S. ENERGY DEMAND AND YET BE LAND, WATER AND NUTRIENT CONSERVATIV ...

    SBIR Phase I 1985 National Science Foundation
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