You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 204651 - 204660 of 207726 results
  1. TOPIC 356: FLUOROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: LUCERNA INC            Topic: NCI

    Circular RNAscircRNAsare a novel class of modified RNAs that are an abundant component of the epitranscriptomePutative functions of circRNAsinclude miRNA sequestrationRNA binding protein scaffoldingmRNA trappingand protein translation regulationDeregulation in one or more of these roles has been linked to several types of cancerOne well studied circRNAciRSis believed to act as a miRNAsponge and in ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 369: NOVEL DOSING AND DISPENSING SYSTEM FOR MULTIPARTICULATE CANCER DRUGS

    SBC: HS-DESIGN, INC            Topic: NCI

    Oncology drugs continue to advance at a rapid pace with many therapies delivered orally as tablets or capsulesSmaller childrenhowevercannot swallow tablets or capsulesFor these drugs to be used in the pediatric population they need to be reformulatedTraditionally this has meant creating a liquid suspensionchewableor rapid dissolve tabletCancer medicationshoweveroften have terrible taste profiles t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. TOPIC #366- PHASE II SBIR CONTRACT- CLONOGENIC HIGH- THROUGHPUT ASSAY FOR SCREENING RADIATION MODULATION

    SBC: SUVICA INC            Topic: NCI

    Clonogenic assays measure the ability of single cells to proliferate and form a colonyThis process approximates closely the regrowth and recurrence of tumors after treatment with radiation or chemotherapyproviding an assay to screen for drugs that block this processYetclonogenic assays are labor intensive and too cumbersome for high throughout screeningHTSof compound librariesHere we propose to de ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC #355- SBIR PHASE II- A 3D PERFUSABLE PLATFORM FOR HTS ACROSS DIVERSE RACIAL/ETHNIC CANCER SPE

    SBC: MIMETAS US, INC            Topic: NCI

    Prostate cancerPCaincidence and mortality in African American men is two times greater than men of other races ethnicities in the United StatesElucidating the underlying mechanisms for this cancer health disparityCHDis critical to patient treatment and improved patient outcomehowever there are no in vitro models available to adequately recapitulate the PCa tumor microenvironment across races ethni ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 368: TREATMENT OPTIMIZATION BY COMBINED A-EMITTER (ARPT)/RADIOTHERAPY (XRT) DOSIMETRY FOR PROSTATE CANCER PATIENTS

    SBC: RADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC            Topic: NCI

    We propose to demonstrate a cloud based software service for Combination alpha emitter radiopharmaceutical therapyRPTand external beam radiotherapyXRTCX RPTtreatment planningBoth modalities deliver radiationWe will demonstrate feasibility clinically by collecting the data needed from an existing Hopkins trial evaluating combination XRT with XofigoRa dichlorideanRPT that concentratesparticle radiat ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC 359: A DEVICE PROTOTYPE FOR ISOLATION OF MELANOMA EXOSOMES FOR DIAGNOSTICS AND TREATMENT MONITORING

    SBC: Aethlon Medical, Inc.            Topic: NCI

    The proposed work aims to develop a pre commercial prototype of an exosome isolation device to be used in clinical diagnostic laboratoriesWe will advance the device to facilitate exosome isolation for downstream liquid biopsy tests requiring analysis of proteinDNAor microRNAwhich rely upon acquisition of intact and pure exosomesThe device strategy will be designed to isolate total exosomes and the ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 360: A SIMPLE END-TO-END SYSTEM FOR SERIAL CELL SORTING AND MANIPULATION USING A SINGLE CONTAINER- MOONSHOT

    SBC: DIAGNOLOGIX, LLC            Topic: NCI

    Chemotherapy may control but rarely cure metastatic cancersRemarkablymodern immunotherapiesincluding cell based therapieshave cured metastatic melanomas and other types of cancersA major challenge for all cell therapies in general is the need to develop cost effective and efficient manufacturing and delivery capabilitiesWe have recently established an innovative cell isolation technology by applyi ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 343: NEUROPSYCHOLOGICAL ASSESSMENT SYSTEM FOR CANCER PATIENTS

    SBC: CREARE LLC            Topic: NCI

    Cognitive decline is a major quality of life concern for many cancer survivorsThevarious available treatments affect individuals differentlyand research has unfortunately provided little guidance on how specific treatments impact neurocognitive functionTo help researchers fill this information gap and ultimately provide guidance to doctors and patientsa neuropsychological assessment system that is ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. TOPIC 366: I-PARTS INTEGRATED PLATFORM FOR ANTI-CANCER RADIATION THERAPEUTICS SCREENING

    SBC: PACT & HEALTH LLC            Topic: NCI

    Tumor Irradiation during cancer treatment induces clonogenic death that can be best assessed by colony forming assaysThese colony forming assays are laborious and never utilized in high throughput screeningHTSformatsWe propose to develop anintegrated platform for HTS clonogenic survival assayfor cancer drug screening as well as radiation effect modulation screeningNamedI PARTSIntegrated platform f ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 353: HIGHLY ACCURATE LOW COST CTDNA DIAGNOSTICS WITH MAGNETIC NANOPARTICLE ENABLED AUTOMATED SAMPLE PREP- MOONSHOT

    SBC: NVIGEN            Topic: NCI

    The goal of the research is to develop a highly accurateautomatedand low cost ctDNA test to monitor efficacy of treatment of metastatic breast cancer patients by identifying the emergence of certain DNA mutations in plasma samplesThere is growing evidence that the presence of certain DNA mutations in the blood stream correlates with breast cancer becoming resistance to hormone treatmentNVIGEN will ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government