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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 205001 - 205010 of 207725 results
  1. ZW800-1: The 1st Zwitterionic NIR Fluorophore for Cancer Imaging & Ureter Mapping

    SBC: Curadel, LLC            Topic: 102

    PROJECT SUMMARY ABSTRACTImage guided surgery using invisible near infraredNIRlight is in the midst of a renaissanceMultiple commercial imaging systemsincluding Curadel s state of the art FLAREsystemare available for preclinicalveterinaryand human surgeryHoweverthe ultimate success of the field will depend on innovative NIR fluorophores that solve important clinical problemsCuradel has invented a n ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Therapeutic antibodies for treating chemotherapy induced peripheral neuropathic pain

    SBC: ABALONE BIO, INC.            Topic: NCI

    ABSTRACT Chemotherapy-induced peripheral neuropathy (CIPN) is an often long-lasting neurological condition that arises frequently in cancer patients who receive broadly used chemotherapies such as taxanes. CIPN causes abnormal pain and other symptoms that can limit chemotherapy dosage and significantly impact quality of life for years. There are no drugs that prevent CIPN or treat it well. Duloxet ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Collaborative Platform for Developing Sepsis Products by Leveraging Sepsis Endotypes Developed Using a Unified Biomarker-Clinical Dataset

    SBC: PRENOSIS INC            Topic: 300

    Principal Investigator/Program Director (Last, first, middle): Reddy, Jr., Bobby Project Summary: Sepsis is a poorly understood clinical syndrome characterized by a dysregulation of the immune system’s response to infection. It is the leading cause of death and is the most expensive condition treated in U.S. hospitals, exerting a $20.3 billion burden in 2011, 5.2% of total costs to the healthcar ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Precision ACS

    SBC: Digital Solid State Propulsion, Inc            Topic: MDA08045

    In process for public release

    SBIR Phase II 2013 Department of DefenseMissile Defense Agency
  5. Clinical Trial of ABC in Patients with Refractory Multiple Myeloma

    SBC: APOGEE BIOTECHNOLOGY CORPORATION            Topic: NCI

    DESCRIPTION provided by applicant Multiple myeloma MM is the second most common hematological malignancy in the United States and remains an incurable disease since nearly all MM patients will eventually relapse and develop resistance to currently available drugs Sphingolipid metabolism is being increasingly recognized as a key pathway in tumor biology In particular sphingosine kinases S ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Whole-organ bioreactor with integrated nondestructive 3D molecular imaging

    SBC: Sonovol, Inc.            Topic: NHLBI

    Abstract Significance: Donor tissue shortage remains a critical problem in lung transplantation. Recent advances in tissue engineering have allowed for the possibility of generating bioengineered lungs from decellularized organ scaffolds. These scaffolds, created from the donor’s tissue, become functionalized after recellularization with a patient’s own cells. However, translation of whole-lun ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of An Underarmor 10 Kilowatt Thermoelectric Generator Waste Heat Recovery System for Military Vehicles

    SBC: HI-Z TECHNOLOGY, INC.            Topic: A03239

    Hi-Z will complete the design of a 10 kilowatt waste heat recovery thermoelectric generator that can be used on the Army’s Stryker and other similar vehicles. One or more advanced quantum well thermoelectric modules with at least three times the efficiency of today’s Bi2Te3 thermoelectrics will be fabricated and tested in the generator. DOD, DOE and NASA presently fund quantum well film develo ...

    SBIR Phase II 2005 Department of DefenseArmy
  8. Non-Invasive Model Attitude and Deformation Measurement

    SBC: Phasespace Inc.            Topic: AF06298

    PhaseSpace's objective is to track the position and attitude of wind tunnel models, along with the wing vibrations and deformations, with minimal modifications to the model. Using a modified PhaseSpace tracking system, and newly developed software, PhaseSpace demonstrated in Phase I that it is possible to track reflective stickers applied to a model from 2 to 3 meter distances with resolutions dow ...

    SBIR Phase II 2007 Department of DefenseAir Force
  9. High-Efficiency Long-Lifetime Neutron Generator For Radiographic Munitions and IED Inspection

    SBC: STARFIRE INDUSTRIES LLC            Topic: A07040

    Sealed-tube fusion neutron generator (FNG) sources have on-off capability and relatively small size suitable for small-footprint neutron radiography (NR) and non-destructive evaluation (NDE) systems; however, lifetime of these tubes at the desired output levels is short (a few hundred hours due to target degradation at high power), and thus have prohibitive operating cost. Starfire Industries pro ...

    SBIR Phase II 2009 Department of DefenseArmy
  10. Point of Care System for Determination of Bilirubin Capacity in Neonates

    SBC: AVIV BIOMEDICAL INC            Topic: 400

    DESCRIPTION provided by applicant Neonatal hyperbilirubinemia occurs in almost all newborns and may be benign if its progression to extreme hyperbilirubinemia is recognized monitored and prevented or managed in a timely manner Neonatal jaundice carries the risk of neurotoxicity due to the deposition of bilirubin in the central nervous system Most of the bilirubin in plasma is bound to pla ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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