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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 205001 - 205010 of 207712 results
  1. VARIABLE COMPLIANCE CHAMBER TO ALTER PULMONARY IMPEDANCE

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A variable compliance chamber (VCC) is proposed to control pulmonary input impedance during the treatment of pulmonary disease. Pulmonary impedance is related to the total work the right heart must pump against, and it is altered (primarily in the form of decreased compliance) in pulmonary disease and in the implantation of oxygenation assisted devices; this i ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  2. AMBULATORY ARTERIOVENOUS CARBON DIOXIDE REMOVAL

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic Obstructive Pulmonary Disease (COPD) affects 15-17 million people in the United States and is the fourth leading cause of death in the U.S. When COPD reaches end-stage, hypercarbia, not hypoxia, usually limits the COPD patients' ability to ambulate. Lung Volume Reduction Surgery remains investigational. Lung transplantation is available to only 900/yea ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  3. Ambulatory Arteriovenous Carbon Dioxide Removal

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): End-stage lung disease from COPD, cystic fibrosis, primary pulmonary hypertension, and ideopathic pulmonary fibrosis affects 15-17 million people in the United States and is the fourth leading cause of death in the U.S. With end-stage lung disease, carbon dioxide retention is a common and grave prognostic sign with limited treatment options. Long-term ventilato ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Simplified Total Liquid Ventilator

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The acute respiratory distress syndrome (ARDS) is a severe, life-threatening disease process that affects approximately 150,000 patients per year with an associated 30-40% mortality rate. Clinical studies are currently exploring the safety and effectiveness of Partial Liquid Ventilation (PLV), in which a perfluorocarbon-filled lung is gas-ventilated, in the ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  5. SIMPLIFIED TOTAL LIQUID VENTILATOR

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    The acute respiratory distress syndrome (ARDS) is a severe, life-threatening disease process, which affects approximately 150,000 patients per year with an associated 30-50 percent mortality rate. Periluorocarbons are inert, colorless, low surface tension liquids that can carry large quantities of oxygen and carbon dioxide. Clinical studies are currently exploring the safety and effectiv ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  6. VARIABLE COMPLIANCE CHAMBER TO ALTER PULMONARY IMPEDANCE

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A variable compliance chamber (VCC) is proposed to control pulmonary input impedance during the treatment of pulmonary disease. Pulmonary impedance is related to the total work the right heart must pump against, and it is altered (primarily in the form of decreased compliance) in pulmonary disease and in the implantation of oxygenation assisted devices; this i ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  7. PAL: Pre-Clinical Fabrication & Outcomes Studies

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): End-stage Lung Disease from all causes is the fourth leading cause of death in the US. Despite the success of lung transplantation, demand for donor lungs has steadily outgrown supply. Currently, the average wait is 2 years, with 30% wait-list mortality. Likewise, acute respiratory distress syndrome (ARDS) is a predominant cause of death in trauma and critic ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. PAL: Pre-Clinical Fabrication & Outcomes Studies

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): End-stage Lung Disease from all causes is the fourth leading cause of death in the US. Despite the success of lung transplantation, demand for donor lungs has steadily outgrown supply. Currently, the average wait is 2 years, with 30% wait-list mortality. Likewise, acute respiratory distress syndrome (ARDS) is a predominant cause of death in trauma and critic ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Enhanced Nitric Oxide-Releasing Materials

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this study is to incorporate nitric oxide (NO)-releasing compounds into polymer formulations that can be used to improve the biocompatibility of blood-contact surfaces in intravascular and extracorporeal devices. Previous studies have demonstrated that coating surfaces with polymer layers that continuously released small amounts of NO inhibited plat ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Enhanced Nitric Oxide-Releasing Materials

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop a family of nitric oxide-releasing materials (NORM), formed by adding nitric oxide (NO) donor compounds to polymers. The enhanced NORM developed in Phase I of this effort relea

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
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