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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 205071 - 205080 of 207714 results
  1. Reducing the incidence of febrile neutropenia in cancer patients treated with chemotherapy with PointCheck: a portable non-invasive neutropenia analyzer

    SBC: LEUKO LABS, INC            Topic: 102

    PROJECT SUMMARY The goal of this Phase II SBIR project is to optimize and validate PointCheck, the first non-invasive point-of-care (POC) device that identifies patients undergoing cancer chemotherapy who have early- stage febrile neutropenia and need immediate treatment to prevent serious infections. Every year in the US, 650,000 cancer patients are treated with chemotherapy. One side effect of t ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  2. In Vivo Proof of Concept and Target Identification Using Small Molecule Stimulators of Brown Adipogenesis

    SBC: ENERGESIS PHARMACEUTICALS INC            Topic: 300

    PROJECT SUMMARY/ABSTRACT Obesity has reached epidemic proportions in the U.S. and plays a major role in the development of type 2 diabetes, dyslipidemia, and cardiovascular disease. There remains a very significant need for better non- surgical treatments. While most current weight loss agents act by suppressing appetite, strategies that can safely enhance energy expenditure have the potential to ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Intranasal Vaccine Against Lyme Disease

    SBC: IMMUNO TECHNOLOGIES INC            Topic: NIAID

    ABSTRACT We propose to develop intranasal, parainfluenza 5 (PIV5) viral-vector delivered vaccines against human Lyme disease (LD) to be administered using a prime-boost schedule, for the US market. A recent new estimate of LD by the CDC places the new number at 476,000 annual cases, up from 329,000 in 2015 which strongly suggests that the number of Americans affected by this vector-borne disease i ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. IGF OT IGF SBIR PHASE II TOPIC TITLE A VASCULARIZED TUMOR MICROENVIRONMENT ASSAY FOR THE SCREENING OF ANTI CANCER DRUGS

    SBC: Nortis, Inc.            Topic: NCI

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Orbital Maneuvering System (OMS)

    SBC: Millennium Space Systems, Inc.            Topic: AF071284

    Millennium Space Systems (“Millennium”) and its partners developed an ESPA-based Orbital Maneuvering System (OMS); a fully functional modular spacecraft with high performance propulsion system capable of delivering Secondary Payloads into tailored orbits. Millennium blends flight proven components and cost saving utilitarian design to meet high value mission requirements at minimal cost and r ...

    SBIR Phase II 2008 Department of DefenseAir Force
  6. Spatial Genomics for in situ single cell expression analysis in the brain

    SBC: SPATIAL GENOMICS, INC.            Topic: 101

    SUMMARY Spatial Genomics, Inc. is commercializing seqFISH technology that can visualize thousands of genes at the mRNA level in single cells with spatial information preserved. Recent advances now make it possible to achieve 10,000 gene multiplexing in single cells directly in tissues (Eng et al., Nature 2019). With this technology, novel cell types can be discovered in situ and spatial organizati ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement

    SBC: POLYNOVA CARDIOVASCULAR INC            Topic: NHLBI

    Project Summary: A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Minimally invasive transcatheter aortic valve replacement (TAVR) has emerged as an effective therapy for the unmet clinical need of inoperable patients with severe aortic stenosis (AS). Recent longitudinal follow-up studies of TAVR patients however indicate that this procedure and associated technology may result i ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Ototoxicity of modified aminoglycosides

    SBC: NUBAD LLC            Topic: NIAID

    PROJECT SUMMARY Aminoglycosides are one of the cheapest and well-known antibiotics in clinical use for over 70 years, but one of the major limitations in their use is their ototoxicity. Although new generations of antibiotics have emerged in the last decades, aminoglycoside antibiotics maintain a leading role in treatment of acute infections and for specific indications such as tuberculosis or the ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. InheRET: A SaaS solution to identify patients at increased risk for hereditary disease.

    SBC: Inheret, Inc            Topic: 102

    PROJECT SUMMARY This project is to expand the InheRET Inherited Risk Evaluation Tool to include recommendations for testing of patients at increased risk for hereditary disease, adding patient navigation features and customizable database entries for healthcare providers. This will include the development, integration and testing of InheRET 3.0 followed by pilot testing in 5 diverse clinics. InheR ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Covering Care: Long-term care planning and education tool for AD/ADRD caregivers

    SBC: MOAI TECHNOLOGIES, LLC            Topic: NIA

    Project Summary/AbstractOlder adults with Alzheimer's disease (AD) and AD-related dementias (ADRD) need a trusted financial advocate to help orchestrate and oversee their care as they age. Spousal and adult child caregivers need comprehensive education around financial caregiving and tools on how to access resources to pay for long- term services and supports (LTSS). This SBIR project will create ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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