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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 205091 - 205100 of 207712 results
  1. Efficient Multitarget Particle Filters for Ground Target Tracking and Classification

    SBC: NUMERICA CORPORATION            Topic: AF04204

    Many factors make the ground target tracking problem decidedly nonlinear and non-Gaussian. Some of these factors include the relatively poor angular accuracy of GMTI sensors, the presence of persistent clutter and target obscuration, and the complexity of target maneuvers. Because these difficulties can lead to a multimodal posterior density, a Bayesian filtering solution is more appropriate ...

    SBIR Phase II 2005 Department of DefenseAir Force
  2. Autologous T-cells Expressing a Chimeric Antigen Receptor Directed to B-Cell Maturation Antigen (BCMA) in patients with Generalized Myasthenia Gravis (MG)

    SBC: CARTESIAN THERAPEUTICS INC            Topic: 102

    Project Summary/ Abstract Myasthenia Gravis (MG), which affects 60,000 people in the U.S., is an autoimmune disease caused by autoantibodies that attack the neuromuscular junction. For many MG patients, there is no safe, selective, and effective therapy, and MG remains a chronic, debilitating, and potentially fatal disease. Today, despite knowledge that the disease is mediated by autoantibodies pr ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid, Point-of-Care Nucleic Acid Test for HCV

    SBC: CROSSLIFE TECHNOLOGIES INC.            Topic: 300

    Rapid, Point-of-Care Nucleic Acid Test for HCV CrossLife Technologies Inc. Project Summary/Abstract Approximately 500 000 people die each year from hepatitis C-related liver diseases [1]. The hepatitis C virus can cause both acute and chronic hepatitis infection [1-2]. Over time, chronic Hepatitis C can cause serious health problems including liver damage, liver failure, and even liver cancer. Ear ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Helium Free MRI Image Guided Radiation Therapy (IGRT) System for ViewRay Inc

    SBC: HYPER TECH RESEARCH INC            Topic: NCI

    ? DESCRIPTION (provided by applicant): This NIH Bridge Grant will result in a conduction cooled, liquid helium free, MRI background magnet for a commercial image guided radiation treatment (IGRT) for cancer treatment. The program will ensure the successful continued commercialization of our customer's image guided radiation therapy (IGRT) system, a vital cancer treatment device now treati ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Helium Free MRI Image Guided Radiation Therapy (IGRT) System for ViewRay Inc

    SBC: HYPER TECH RESEARCH INC            Topic: 102

    DESCRIPTION provided by applicant This NIH Bridge Grant will result in a conduction cooled liquid helium free MRI background magnet for a commercial image guided radiation treatment IGRT for cancer treatment The program will ensure the successful continued commercialization of our customerandapos s image guided radiation therapy IGRT system a vital cancer treatment device now treating p ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR TOPIC 417: QUANTITATIVE IMAGING SOFTWARE TOOLS FOR CANCER DIAGNOSIS AND TREATMENT PLANNING

    SBC: NEURALRAD LLC            Topic: 417

    With brain metastases (BMs) incidences rapidly increasing due to improved systemic treatment and cancer patients, survival, the BMs management strategies have evolved substantially from whole brain irradiation to localized multisession SRS. The evolution requires contouring and distributed SRS planning for multiple BMs and treatment followups and has put a high demand on care teams time, efforts, ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Automated System for High Yield Pancreatic Islet Isolation

    SBC: CG SCIENTIFIC INC            Topic: 200

    Project Summary/Abstract This Phase II project aims to develop an automated system for high-yield pancreatic islet isolation for use in islet transplantation (an emerging therapy for type 1 diabetes) and diabetes research. The effectiveness of islet transplantation relies critically on the quality and quantity of the transplanted islets, which are isolated from deceased human donor pancreata. Howe ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  8. Diagnostics Development and Novel Technology Development and Evaluation to Improve Diagnostic Testing Capabilities for COVID-19 Detection

    SBC: BOTANISOL ANALYTICS, INC.            Topic: AF20RDCSO1

    The Department of the Air Force (AF) Small Business Innovation Research (SBIR) program has established a Direct to Phase II X20.R SBIR Commercial Solutions Opening including a specific call for Approach 5b: COVID Testing Field Deployable Test Kit (no refrigeration). Botanisol Analytics has long been engaged in the development of molecular diagnostic tools for data collection including virus screen ...

    SBIR Phase II 2020 Department of DefenseAir Force
  9. Development of a PO-administered beta-lactam-tarocin combination agent to treat methicillin susceptible and methicillin resistant Staphylococci

    SBC: Prokaryotics, Inc.            Topic: NIAID

    The goal of this SBIR Phase IIB proposal is to develop a novel tarocin/-lactam combination agent suitable for oral administration which could be used to safely and effectively treat patients infected by methicillin-susceptible and resistant Staphylococcus aureus and Staphylococcus epidermidis (MSSA, MRSA, MSSE and MRSE). MRSA and MRSE are a major cause of bloodstream infections in the hospital ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Preclinical Development of Full Length Single Chain

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The positive outcome of the RV144 Phase III vaccine trial (the Thai trial ) that tested an ALVAC-HIV/AIDSVAX B/E prime/boost protocol has prompted the field to refocus on humoral immunity as a means of achieving sterilizing immunity. This has also renewed interest in positioned other envelope-based subunit immunogens that may provide a better booster to achiev ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
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