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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 205181 - 205190 of 207731 results
  1. Creation and Validation of the Dose-Opioid-Source Evaluation tool (DOSE)-a Robust Opioid Use Clinical Outcome Assessment for Qualification as an FDA Medical Device Development Tool (MDDT)

    SBC: MMJ Labs, LLC            Topic: NIDA

    Project Summary This project will develop a Clinical Outcome Assessment (COA) for the FDA’s Medical Device Development Tool (MDDT) program assessing patient-reported outpatient opioid use, then calculating the gold standard metric of milligrams of morphine equivalents (MME) using the CDC MME Conversion dataset. In the qualified context of use of a clinical trial with informed consent to report a ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. New 5HT2AR Target Identification and Assay Development for Discovering Psychoplastogenic Compounds

    SBC: BIOINVENU CORPORATION            Topic: NIDA

    Specific Aim: New 5HT2AR/14-3-3 isoform signal pathway identification and assay development for discovering psychoplastogenic compounds. Significance: Emerging data and limited clinical results show the promise of psychedelic drugs in the durable relief of people from seemingly untreatable psychiatric disorders and drug addictions. Neuroimaging evidence supports the concept that the brain after a ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Long-acting injectable ketamine for improved substance use disorder (SUD) treatment without dissociative effects.

    SBC: CONSEGNA PHARMA INC            Topic: NIDA

    PROJECT SUMMARY / ABSTRACT There are more than 22 million individuals in the United States with a substance use disorder (SUD). SUDs are a collection of chronic disorders often characterized by drug-seeking behavior manifesting as a cycle of substance intoxication and binging, followed by withdrawal, and craving states that contribute to compulsive relapses, often driven by non-compliance with tre ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Determination of Route of Administration and Cardiac Safety of a Novel Psychoplastogen for the treatment of SUDs

    SBC: DELIX THERAPEUTICS INC            Topic: NIDA

    ABSTRACT Delix Therapeutics is developing psychoplastogens, compounds that promote rapid and sustained neuroplasticity. This new class of compounds was identified by Delix founder, Professor David Olson (UC Davis). DLX-007 is a novel, potent psychoplastogen designed and inspired by known psychoplastogens Ibogaine and 5-MeO-DMT. Similar to these clinically effective compounds, DLX-007 promotes stru ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Video observed therapy to enhance flexibility and reduce in-person visits for patients treated with methadone in a multi-site opioid treatment program

    SBC: EMOCHA MOBILE HEALTH INC.            Topic: NIDA

    PROJECT SUMMARY The COVID-19 pandemic intersecting with the opioid epidemic led to dramatic shifts in the delivery of care for opioid use disorders (OUD). Historically, methadone has been provided as directly-observed therapy (DOT) at opioid treatment programs (OTPs). This model of care delivery has been a barrier to accessing care due to imposed travel burden and disruption to work and family res ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. SafeMedWaste At-Home, Environmentally-Friendly Opioid Disposal Kit for Orthopedic Post-Operative Surgical Patients to Reduce Opioids Available for Diversion

    SBC: Okra Medical, Inc.            Topic: NIDA

    Knee and shoulder surgery patients are at high risk of becoming addicted to opioids that are prescribed to manage pain after their surgery. Each year, from the 1.475 million knee/shoulder surgeries performed in the United States, an estimated 167,000 people, and another 17,000 of their friends and family, will become addicted to opioids. Limited options for disposal of unused opioids, such as drug ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. A Rugged, Reliable, Portable, Safe, and Simple Naloxone HCl Auto-Injector forLife-Saving Treatment of Opioid Overdose

    SBC: PIROUETTE MEDICAL, INC.            Topic: NIDA

    Project Summary From 2019 to 2020, overdose deaths in the US increased by 30% year on year; 187 people die each day from opioid overdose in the US. Naloxone has significantly decreased opioid mortality with increased usage as a first line life-saving measure prior to emergency help and hospitalization. Naloxone HCl Injection, USP (Naloxone) is an opioid antagonist that rapidly reverses overdose an ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Engineering the Mesh, Cold Weather Baselayer Undershirt and Drawer with Seamless Knitting

    SBC: PROPEL, LLC            Topic: N231002

    Propel proposes to conduct research in order to determine the performance level of a seamless cold weather mesh undershirt and drawers as compared to the existing undershirt and drawers.  Propel shall develop initial concepts and evaluate their technical feasibility.  Comparison to conventionally sewn seams using internationally recognized standards and test methods, as well as novel test method ...

    SBIR Phase I 2023 Department of DefenseNavy
  9. A comparative study of seamless versus traditional seamed mesh garments utilizing industry standard state-of-the-art knitting machinery

    SBC: INNOVAKNITS, LLC            Topic: N231002

    Innovaknits, LLC (IK) is a contract manufacturing company specializing in flatbed knitting. We have both product development and production services located in Conover, NC. IK will collaborate with North Carolina State University’s Wilson College of Textiles (NCSU), specifically Zeis Textile Extension (ZTE), as a subcontractor, focusing on their extensive knitting laboratory and physical textile ...

    SBIR Phase I 2023 Department of DefenseNavy
  10. Seamless Knitted Mesh, Cold Weather Baselayer Undershirt and Drawer

    SBC: TDA RESEARCH, INC.            Topic: N231002

    Cold weather baseylayers are crucial to protecting warfighters from cold injury. Current military baselayers are produced using cut and sew methods that create a long supply chain that require multiple production steps and a significant amount of human labor. This makes ensuring Berry compliance challenging. It is critical for supply chain security for the US to develop a larger textile industry t ...

    SBIR Phase I 2023 Department of DefenseNavy
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