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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 205281 - 205290 of 207712 results
  1. TOPIC 403: DEVELOPMENT OF SPATIAL MICROPURIFICATION TECHNOLOGY

    SBC: AVONEAUX MEDICAL INSTITUTE, LLC            Topic: 403

    The tumor microenvironment (TME) comprises a mixture of cell types, including tumor cells, cancer sub-clones, metaplasia, dysplasia, desmoplasia, reactive fibroblasts, and a complex immune response. Measuring the molecular status of each cellular component within the TME is important to understanding tumor initiation and progression as well as in determining the interplay between cancer and normal ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Hardware Based Broadband Ultra High-speed Digital Signal Processor

    SBC: S2 CORP            Topic: AF112142

    ABSTRACT: S2 Corporation and subcontractor Research Associates of Syracuse aim to develop a broadband hardware-based ultra high-speed signal processor for real time digital, broadband RF spectrum over 2-18 GHz with digital signal stream captures and analysis for a countermeasure applications, and to demonstrate these digital algorithms to significantly advance the tactical capability through comp ...

    SBIR Phase II 2013 Department of DefenseAir Force
  3. nForge: A Multi-Model Framework for System Designers

    SBC: EFFECTIVE AUTOMATION SYSTEMS, INC            Topic: AF141056

    ABSTRACT: Enhanced Modeling and Analysis of embedded real-time systems is vital to prevent late stage architecture changes, which can be costly from program risk and cost perspectives. System designers use various standards for modeling, including UML and SysML with MARTE augmentations, with supporting tools. These do not integrate well with specialized tools - e.g., for schedulability, performanc ...

    SBIR Phase II 2015 Department of DefenseAir Force
  4. Development of a chemical reaction sensor array platform for label-free, real-time kinetic analysis of enzyme-substrate reactions to enable high-throughput drug discovery

    SBC: SPOC PROTEOMICS INC.            Topic: NCATS

    Project SummaryGlobal expenditures by pharmaceutical companies for research and development continue to increase each year with a current estimate of $1B USD and upwards of 15 years to develop a new drug. Drug discovery efforts are critical to the downstream success of candidate selection and relies heavily on high-throughput screening (HTS) to identify viable leads. Current methods for HTS drug d ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Commercialization of cavitation-enhancing nanodroplets for DNA sample fragmentation in NGS applications

    SBC: Triangle Biotechnology, Inc.            Topic: 102

    PROJECT SUMMARYThe completion of the Human Genome Project has established NGS as the gold standard technology for personalized/precision medicine and diagnostics. Genetic testing kits are now as readily available as pregnancy test kits, and advances in genetic analysis, gene therapy, and genetic modification in the 21st century promise to parallel the development of transistors and integrated circ ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Model-based Adaptive and Intelligent Naval Training for Operational Readiness (MAINTOR)

    SBC: QUALTECH SYSTEMS, INC.            Topic: N192124

    Qualtech Systems, Inc. (QSI), Aptima, Inc., Huntington Ingalls Industries (HII) and the Hess PHM Group have partnered, with QSI as the prime, to address the key objectives of this solicitation and provide MAINTOR, a robust, intuitive, versatile and flexible digital twin-driven maintenance training tool that include a rich, immersive and learning-science enabled user experience. MAINTOR is levera ...

    SBIR Phase II 2020 Department of DefenseNavy
  7. Automatic Real-Time Magnetometer Error Compensation and Calibration

    SBC: TIAX LLC            Topic: A05213

    TIAX proposes to develop a solid state heading sensor to meet Navy towed array requirements.

    SBIR Phase II 2010 Department of DefenseNavy
  8. A turnkey research platform to accelerate clinical translation of targeted immune-modulation enhanced therapies

    SBC: Sonovol, Inc.            Topic: 102

    Abstract Focused ultrasound (FUS) is an early-stage, noninvasive technology with great therapeutic potential in oncology and other diseases. FUS offers either an alternative or complementary strategy to existing cancer treatment approaches such as surgery, radiation, drug delivery, and immunotherapy (immuno-oncology, or “IO”). Most recently, IO specifically has demonstrated enormous potential ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  9. 3D Acoustic Model for Geometrically Constrained Environments

    SBC: HEAT, LIGHT, AND SOUND RESEARCH, INC.            Topic: N16AT018

    Systems that operate in constrained environments depend on the acoustics in several ways. Harbor defense systems detect intruders (peopleand/or vessels) by either listening for their noises (passively) or by pinging on them and detecting their echoes (actively). Furthermore, suchsystems may also form the equivalent of an underwater cell phone network using sound to carry the information. The acous ...

    STTR Phase II 2017 Department of DefenseNavy
  10. Personalized, Easy-To-Use Tool for AD/ADRD Caregivers Addressing Financial Management and Legal Planning

    SBC: Minnesota HealthSolutions Corporation            Topic: R

    Project Summary/Abstract We propose to develop an innovative tool to aid caregivers of persons with Alzheimer’s disease (AD) and AD- related dementias (ADRD) in obtaining guidance for appropriate financial management and legal planning. Financial management is one of the two most cited sources of significant stress among caregivers. Legal planning, while often enjoined with financial management, ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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