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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Sensitive Detection of Bacterial Contamination in Platelets

    SBC: LYNNTECH INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Bacterial contamination of platelets is the leading cause of morbidity and mortality from a transfusion- transmitted infection. Bacterial contamination rates for platelets have been estimated to occur at a frequency of 1 in 2,000 to 1 in 3,000 platelet units. Projected fatalities from these transfusions, based on extrapolation from surveillance and other studie ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Sensitive expression profiling in fixed archived tissue

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Archives of formalin-fixed paraffin embedded (FFPE) human histological tissue samples, probably numbering in the millions of tissue blocks, constitute a tremendous, yet underutilized, historical resource for studying gene expression changes associated with human disease states. Unlike freshly acquired samples, there is usually greater documented medical hist ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Sensitive, Quantitative, and Portable Anatoxin Assay using Aptamers and Quantum Dot Nanoshell Reporting

    SBC: Biotex, Inc.            Topic: N/A

    This proposed project directly addresses an U.S. Environmental Protection Agency (EPA) calling for improved detection and measurement techniques including screening kits for algal neurotoxins (especially cyanobacterial anatoxin) and cytotoxins in drinking water systems. Bloom-forming cyanobacteria have been observed in water bodies, including drinking water reservoirs all over the world. Several ...

    SBIR Phase I 2008 Environmental Protection Agency
  4. Sensitive, Quantitative, and Portable Anatoxin Assay using Aptamers and Quantum Dot Nanoshell Reporting

    SBC: Biotex, Inc.            Topic: 07NCERD1

    This proposed project directly addresses an U.S. Environmental Protection Agency (EPA) calling for “improved detection and measurement techniques including screening kits for algal neurotoxins (especially cyanobacterial anatoxin) and cytotoxins in drinking water systems.” Bloom-forming cyanobacteria have been observed in water bodies, including drinking water reservoirs all over the world. Se ...

    SBIR Phase I 2008 Environmental Protection Agency
  5. SensiTrak: Automated Assessment of Forelimb Sensation

    SBC: VULINTUS, INC            Topic: 106

    Project Abstract In this Phase I STTR project, Vulintus, Inc., in collaboration with Columbia University, proposes to develop and test ‘SensiTrak,’ an automated, high-throughput behavioral system designed to finely measure somatosensory function in rodent models. Current common methods for measuring somatosensory function in rodent models generally rely on withdrawal responses to uncomfortable ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Separation of Sr-90 and Ca2+ in Enviromental Samples

    SBC: LYNNTECH INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this SBIR project is the development of an improved inorganic ion exchanger with an extremely high selectivity for Sr2+. This ion exchanger will improve the extraction of 90Sr from groundwater at the sites around the US and the world that have become contaminated through mishap or poor handling of nuclear materials, some of which are in contact with ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Separation of Sr-90 and Ca2+ in Environmental Samples

    SBC: LYNNTECH INC.            Topic: N/A

    This small business innovation research Phase I project will utilize the controllable ion exchange properties of mixed metal oxides to efficiently separate radiostrontium from calcium (and other alkaline earth metals). The ion exchange properties of hydro

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Sequence enrichment of long DNA to enable new modes of genomic analysis

    SBC: PETAOMICS, INC.            Topic: 172

    Sequence enrichment of long DNA to enable new modes of genomic analysis SBIR grantProject Summary Abstract The assembly of phased maternal and paternal haplotypes from human genomic DNA is compromised when short DNA fragments are used for sequencingThe analysis of DNA methylation modifications is also severely compromised when short DNA is sequencedA technology recently developed by PetaOmicsIncen ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Sequencing of Epigenetic Modifications from Single Cells

    SBC: BIOO SCIENTIFIC CORPORATION            Topic: 172

    DESCRIPTION provided by applicant DNA methylation has been shown to be associated with cancer inflammatory and metabolic disorders neuronal plasticity and memory formation Up to now DNA methylation has been largely studied by whole genome bisulfite sequencing of populations of cells Studies like the Epigenomics Project and the Genomes Projects have contributed significantly to our und ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Service and Software Solution for the Rigorous Design of Animal Studies

    SBC: SERALOGIX, LLC            Topic: NIDA

    DESCRIPTION The primary goal of this fast track project is to commercialize a cloud based software suite complemented with on call expert services to guide life science researchers that may have minimal statistical and experimental design ED knowledge to rigorously plan optimize justify manage and report results for complex animal studies Inadequately planned experiments e g lack of r ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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