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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Evaluating Synthetic Biology Produced Triterpene Oils in Adjuvant Formulations

    SBC: Enepret Incorporated            Topic: NIAID

    ABSTRACT Vaccine adjuvants help stimulate the body to generate an immune response when co injected with an antigenthe compound for which immunity is desiredAlthough the human body is capable of producing antibodies to most injected antigensadjuvants can help boost the body s ability to mount a successful and acquired immune response to the presented targetAdjuvants have been shown to enhance immun ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Using advanced natural language processing to facilitate documentation of meaningful use and quality payment compliance

    SBC: Safermed, LLC            Topic: NLM

    PROJECT SUMMARY The Center for Medicare and Medicaid Services Quality Payment Program is designed to motivate healthcare providers to adhere to best practices in clinical healthcare and patient safetyUnfortunatelyextracting quality measures data from the clinical record is burdensome and as suchparticipation among clinical healthcare providers is suboptimalOur aim is to develop a system to facilit ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Toward Automated Spike Sorting via Ground Truth Neural Recordings

    SBC: Leaflabs, LLC            Topic: 101

    PROJECTSUMMARY Scaling extracellular electrophysiology to higher channel counts is hindered by the burden of data handling storageand especially preprocessinge gspike sortingThe burden of spike sorting can in principle be reduced through a combination of high density multielectrode arrayprobetechnology and algorithm optimization to yield a spike sorting method that is both highly accurate and full ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. An integrated neural network analysis and video microscopy platform for fully automated particle tracking

    SBC: AI Tracking Solutions LLC            Topic: 400

    Project Summary AbstractParticle trackingPTis a biophysical tool for elucidating molecular interactionstransport phenomena of diverse speciesand rheological properties of complex materialsPT experiments involve first obtaining high resolution videos that capture time resolved increments of particlesfollowed by extraction of traces of entities of interest from videos in the form of spatial location ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Insightful Surgical Vision Technology (ISVision) for intelligent real-time display of anatomic, physiologic, and pathologic information in surgery

    SBC: Activ Surgical Inc            Topic: NIBIB

    Abstract Intelligent intraoperative display of anatomic and physiologic information coupled to real time situational awareness to critical tissues will benefit all surgeryThe current surgical vision is limited to naked human eyes in open surgery or more recently using laparoscopic digital imaging for minimally invasive surgery and robot assisted surgeryIn laparoscopic visionalthough the visualizat ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Mobile Tai Chi Platform for Fall Prevention in Older Adults

    SBC: BIOSENSICS LLC            Topic: NIA

    Project Summary The overall goal of the proposed work is to develop a platform capable of delivering and monitoring adherenceproficiencyand safety of a home based simplified Tai Chi intervention for older adultsDuring Phase I of this Fast Track STTR project we will further develop a novel approach to assessing Tai Chi performance adherenceproficiencyand safety based on wearable sensor dataMetrics ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment

    SBC: APPLIED UNIVERSAL DYNAMICS, CORP            Topic: NIA

    Project Summary Abstract This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Chemical Libraries Targeting Epigenetic Methyl Writers and Erasers

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYIn this proposalEpiCypher is partnering with DrJian Jina leader in medicinal chemistry and epigenetic drug discoveryto develop the first epigenetics focused chemical library for histone methylationSmall molecule inhibitors that target histone methylation are an emerging class of therapeutics for cancer treatmentThis hot bed of drug development is fueled by the identification of nume ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Fluorescent nanofoldamers for multiplex flow cytometry

    SBC: Nirvana Sciences, Inc.            Topic: 400

    PROJECT SUMMARY ABSTRACT Polychromatic flow cytometryFCis one of the most powerful analytical techniques used in immunologybasic researchand clinical medicineIn basic researchFC is a primary tool for understanding disease development at the cellular and subcellular levelsIn the rapidly developing field of immunotherapyFC is an indispensable tool for monitoring the effectiveness of new therapies an ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Non-Opiate Topical Formulations for Treating Pain Associated with Molar Extractions

    SBC: ARCATO LABORATORIES, INC.            Topic: NIDCR

    Project Summary Abstract Most of the deaths from drug overdoses are driven by synthetic opioidsDentistry highly contributes to the opiate addiction epidemicFollowing dental surgeryof oral surgeons prescribe opiatesand most opiates are prescribed after wisdom teeth extractionthird molarto reduce pain caused by dry socketsApproximatelymillion surgical tooth extractions are performed onmillion patien ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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