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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A universal mechanobiology tool for drug discovery in lung diseases

    SBC: Mechanobiologix L.L.C.            Topic: NHLBI

    Abstract Despite significant effortsno cure exists for the major respiratory diseases such as asthmaemphysema and pulmonary fibrosis due to a lack of proper preclinical methodsDrug development is often carried out in cultured cellsWhile amenable to imaging and manipulationthis approach lacks the native tissue environment and neglects the effects of mechanical forces due to breathing which influenc ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A universal vaccine for the prevention of meningococcal meningitis in Africa

    SBC: OMVAX INC            Topic: R

    For more than years sub Saharan Africa has suffered with high rates of endemic meningococcal disease and periodic epidemic epidemics involving over cases In a low cost serogroup A polysaccharide protein conjugate vaccine MenAfriVac was introduced in the region The vaccine confers protection against serogroup A MenA disease as well as asymptomatic nasopharyngeal MenA carria ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A user-friendly microfluidic chip for anti-epileptogenic drug screening

    SBC: Xona Microfluidics, Inc.            Topic: 101

    New pharmacological treatments for epilepsy will be discovered through the development of new screening platforms that are rapidreliableand can identify novel disease modifying therapiesor anti epileptogenic treatmentsXona MicrofluidicLLCXonais in a unique position to provide such screening tools and services for epilepsy researchXona focuses on the development of microfluidic platforms for neuron ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A user-friendly scalable microfluidic platform for enhanced neuron-cell culture

    SBC: Xona Microfluidics, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): Neuron-cell culture is widely used for studies in basic research, drug discovery, and toxicity testing. Traditional random cultures allow limited access to subcellular compartments (axons, dendrites, synapses) due to extensive and haphazard growth of neurons. Our long-term goal is to provide robust, user-friendly, and cost effective culture platforms that can o ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. A user-friendly scalable microfluidic platform for enhanced neuron-cell culture

    SBC: Xona Microfluidics, Inc.            Topic: 101

    DESCRIPTIONprovided by applicantNeuron cell culture is widely used for studies in basic researchdrug discoveryand toxicity testingTraditional neuron cell culture approaches result in random growth of processes which prevent the study of their unique polarized morphologyOur goal is to provide robustuser friendlyand cost effective culture platforms to manipulate and access neurons and their subcellu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Auto-antibody profiling of non-small cell lung cancer

    SBC: 20 20 Genesystems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Tumor markers, measured in peripheral blood, could assist in diagnosis and management of non-small cell lung cancer (NSCLC) and potentially improve historically dismal outcomes. Circulating antibodies, generated to a wide range of tumor-associated proteins, can be translated into a valuable blood test for lung cancer. Preliminary data supports this hypothesis. ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Auto-BioFeedback and Health Monitoring System for People with Minor Cognitive and

    SBC: BIOSENSICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This project will develop and commercialize a reliable and interactive auto-feedback system for tele-care of persons with minor cognitive impairments (MCIs), such as Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD), or short-term memory loss. The proposed system, which integrates MEMS-based sensor technology with an interactive bio- feedback ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Automated analysis of skeletal muscle fiber crossectional area and metabolic type

    SBC: VALA SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The accurate quantification of skeletal muscle morphology is desired by researcher investigating a wide variety of health issues such as aging, muscle denervation, muscle regeneration, muscular dystrophy, exercise p hysiology, nutrition, and space flight. For such studies, tissue sections prepared from skeletal muscle samples are fixed, stained to visualize ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Automated Analysis of Skeletal Muscle Fiber Cross-sectional Area and Metabolic Ty

    SBC: VALA SCIENCES, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): The accurate quantification of skeletal muscle morphology is desired in a wide variety of medical areas such as muscle regeneration, muscular dystrophy, exercise physiology, and nutrition. For such studies, skeletal muscle is often fixed, sectioned, and labeled to visualize the borders of the muscle fibers, and digitally photographed. Investigators then use lab ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Automated Dynamic Lists for Efficient Electronic Health Record Management

    SBC: Clinacuity, Inc            Topic: NCI

    DESCRIPTION (provided by APPLICANT): Medical errors are recognized as the cause of numerous deaths, and even if some are difficult to avoid, many are preventable. Computerized physician order-entry systems with decision support have been proposed to reducethis risk of medication errors, but these systems rely on structured and coded information in the electronic health record (EHR). Unfortunately, ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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