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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. In Vivo Studies of a Novel HDAC Inhibitor for Treating Hemoglobin Disorders

    SBC: CETYA THERAPEUTICS, INC.            Topic: NHLBI

    PROJECT SUMMARY The β-hemoglobinopathies are prevalent genetic blood diseases with few treatment options. It is estimate that 7% of the worldandapos;s population carries an abnormal hemoglobin gene with 400,000 infants born annually with a severe life threatening hemoglobinopathy. Drug mediated induction of normal, but developmentally silenced, fetal hemoglobin (HbF) expression reduces anemia and ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Learner Engagement and Motivation to Learn Assessment and Monitoring System

    SBC: Design Interactive, Inc.            Topic: AF17AT009

    Training can now be delivered on a large scale through emerging platforms, but training must be engaging to be effectively utilized. Key to providing training that makes a difference in the field is an understanding of how to induce high levels of engagement during learning and the ability to objectively assess engagement in real-time so that interventions can be tailored during training to optimi ...

    STTR Phase II 2019 Department of DefenseAir Force
  3. LEARNING-BASED APPROACH FOR RELEVANT DATA EXTRACTION (LARDE)

    SBC: ROBOTIC RESEARCH OPCO, LLC            Topic: N13AT016

    Autonomous systems continue to be outfitted with larger amounts of sensors that are capable of collecting extremely large amounts of data over the course of a mission. Even autonomous systems with high storage capacities can run into storage limitations when burdened with large amounts of sensor data over long mission durations. This proposal will develop a Learning-based Approach for Relevant Dat ...

    STTR Phase I 2013 Department of DefenseNavy
  4. Learning System for Continuous Professional Education in Low Vision Rehabilitatio

    SBC: Emerald Events, Inc.            Topic: NEI

    Emerald Education Systems has developed an online continuing professional education learning system that targets low vision rehabilitation service providers. This CE learning system has three components: 1) a set of coordinated in depth online courses that provide a broad and deep foundation of knowledge on low vision rehabilitation that is delivered using a didactic approach at a learner-controll ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Lentiviral gene therapy for mucopolysaccharidosis

    SBC: LENTIGEN CORPORATION            Topic: NIDDK

    DESCRIPTION (provided by applicant): Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked recessive inherited disorder caused by absence of iduronate-2-sulfatase, resulting in systemic accumulation of glycosaminoglycans heparan sulphate and dermatan sulphate. Affected individuals suffer from skeletal abnormalities, organomegaly, life- threatening obstructive airway disease, and, ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Lentiviral-MGMT gene transfer into hematopoietic stem cells

    SBC: LENTIGEN CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Therapeutic stem cell gene transfer relies on long-term gene expression achieved by integration of new DNA into the cellular genome. Current clinical trials featuring oncoretroviruses have encountered a number of roadblocks that include low levels of gene transfer, poor expression, and a recognized preferential insertion near promoter regions that increases the ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Limit State Design of Composite Aerospace Structures

    SBC: CORNERSTONE RESEARCH GROUP INC            Topic: ST13A006

    Federal Aviation Administration Advisory Circular 20-107B provides guidance on the achievement of compliance with Title 14 of the Code of Federal Regulations regarding airworthiness type certification requirements for composite aircraft structures necessi

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  8. Live-Cell Fluorescence Lifetime FRET Assays for HTS

    SBC: Fluorescence Innovations, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): This project will establish proof-of-concept for a powerful and versatile implementation of live-cell assays in a true high-throughput screening (HTS) format for small-molecule drug discovery. The technological basis isfluorescence lifetime (FLT) readout of FRET between fluorescent fusion proteins. Lifetime measurement is needed in HTS to overcome the low preci ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Local Navigation in GNSS and Magnetometer-Denied Environments

    SBC: PRIORIA ROBOTICS HOLDINGS, INC.            Topic: T501

    The proposed solution exploits recent advances in computer vision to conceive of a single-camera + gyro + accelerometer vision-based navigation solution such that the processing will be lightweight (requiring only a single optical flow sample per frame). Known landmarks (natural or artificial) will have absolute positions known to planetary exploration worker robots. The worker robot can identif ...

    STTR Phase I 2013 National Aeronautics and Space Administration
  10. Low-Cost Ball/Air/Magnetic Hybrid Bearing System for Extended-Life Micro Gas Turbine Engines

    SBC: Nastec, Inc.            Topic: N10AT037

    A unique type of air lubricated thrust bearing called a Wave Bearing is proposed to assist a rolling element bearing to carry the thrust load and to improve the bearing’s life when used in a micro gas turbine engine. The Wave Bearing technology will provide improved reliability, safety and life compared to rolling element bearings used alone, as well as to allow simplification of engine design a ...

    STTR Phase I 2010 Department of DefenseNavy
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