Award Data

Cancer care coordination entails complex decision making multiple handoffs between primary and specialty care providers and coordination among cancer care team members To manage this complex set of oncology data and workflows EHRs and other health IT systems such as health information exchanges are well suited and have the potential to facilitate information flow between health plans provid ...

SummaryNew treatments are needed for severe asthmatics who do not respond to standard therapy with inhaled steroids especially those with a type low phenotype such as individuals with neutrophil predominant inflammation This solicitation is for the development and early commercialization of an inhalational formulation of the A apolipoprotein A I apoA I mimetic peptide that can be adminis ...

PROJECT SUMMARY ABSTRACT The overall goal of this project is to develop a human protein that is an inhibitor of galectin as a biologic to aid in the prevention and treatment of harmful remodeling after myocardial infarction MI heart attack and thereby improve cardiac function and reduce mortality from subsequent heart failure MI is the most common cause of cardiac morbidity and mortality ...

Many pipelines within America’s infrastructure are in dire need of repair, due to structural damage caused by corrosion, or the threat of heavy metal leaching from lead and copper pipes. However, full pipe replacement is expensive and disruptive, while existing polymer liners and sleeve inserts can only_x000D_ be applied in specific cases and have difficulty bonding to worn and contaminated surf ...

Project Summary The broad long term objective of this Fast Track proposal is to develop an innovative self management intervention SMI technology Inspiration Point for the treatment and study of Chronic Obstructive Pulmonary Disease COPD This application directly addresses the NHLBI SBIR requests for proposals for the development of innovative technologies for COPD the development of techn ...

Abstract Combinati is looking to bring an integrated digital PCR platform with injection molded microfluidic consumables from lab to marketplace to advance the biomedical research Digital PCR has drawn attentions in both genomic research and clinical research communities for its ability to detect rare events high sensitivity less prone to inhibition high specificity no need for an internal ...

Summary Technology for studying the higher order structure HOS of biomolecules encompasses some of the most important tools in all of science and is a highlighted NIGMS research topic Mass spectrometric methods for studying HOS include oxidative footprinting and other methods to covalently label amino acid side chain functional groups and also hydrogen deuterium exchange HDX on protein bac ...

Summary The use of mass spectrometry MS for quantitative protein characterization has increased dramatically identifying and quantifying thousands of proteins is no longer a heroic task nor is characterizing therapeutic proteins in detail Due to widely available software quantitative mass spectrometry has become routine and widely used for addressing questions in basic biology translational ...

In prior research and development, the project team developed LiveSchool, an online platform to track student behavior. With this Phase I funding, the team will develop and test a prototype of an administrator dashboard. The dashboard will generate reports on individual student behavior patterns across classes and on the prevalence of behavioral issues across different teachers. The dashboard will ...

DESCRIPTION provided by applicant An estimated million people have Alzheimerandapos s Disease AD In the United States one in adults over has dementia By this number is predicted to grow to million people The silver tsunami is coming each aging adult could benefit from understanding their cognitive status so that they can make appropriate preparations for their care The c ...