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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Developmental Disabilites Early Intervention Training

    SBC: PRAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Federal and state laws require that young children with disabilities or who are at risk for developing disabilities be provided with Early Intervention services according to their developmental needs. But currently ther e is a critical shortage of skilled EI providers. The primary reason for this shortage is a lack of educational and training programs. Except f ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. A multimodal platform for Oral screening of COVID-19

    SBC: InnoTech Precision Medicine, Inc            Topic: NIDCR

    Original Abstract A multimodal platform for Oral screening of COVID-19 The development of a rapid and reliable sensor system from readily available oral specimens is crucial for the screening and management of SARS-CoV-2 infection. Other than tests that require laboratory-scale instrumentation, the development of rapid tests can play a timely role in the management of an outbreak. Current rapid te ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Gradient Coils to Enhance MRI Research in Mental Health

    SBC: INSIGHT NEUROIMAGING SYSTEMS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In Phase I of this STTR it was shown that it is technically feasible to substitute a planar gradient coil design for the conventional cylindrical coil design to provide greater working space inside magnetic resonance scanners. The planar gradient coil design increases the research potential of hundreds of small-bore ultra-high field scanners to include a var ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Identification of Novel ACTH Small Molecule Antagonists

    SBC: Chemdiv, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of drugs based on the MC2R antagonists will directly benefit children with CAH and Cushing's diseases, and will help us to understand MC2R's role in metabolic pathways. The long term goal of this project is to discover small molecule inhibitors of MC2 receptor and develop drug to treat several metabolic diseases including CAH and Cushing's diseases ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Isotopically Labeled Nucleotides for Biomolecular NMR

    SBC: CASSIA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed research is to scale up the production and manufacture of high-value ribonucleoside triphosphates containing stable isotope labels. The use for these products is in biomolecular studies of RNA structure using Nuclear Magnetic Resonance (NMR) spectroscopy. The market for these products is structural biology groups in academic and industr ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Homogeneous Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to provide a homogeneous, closed-tube system for DNA mutation scanning on a high-throughput platform. For many complex genetic diseases, it is very difficult and expensive to screen for all possible mutations that may cause the disease. We propose a relatively simple solution. Certain dyes are compatible with PCR and can detect sequence alterat ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. A System for Rapid PCR, Mutation Scanning and Genotyping

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to provide a closed-tube system for rapid PCR, mutation scanning and genotyping that does not require fluorescently-labeled probes. For many genetic diseases, it is difficult and expensive to screen for all possible mutations that may cause the disease. We propose a relatively simple solution for rapid amplification, scanning and genotyping in ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Snapback Primers for Genotyping and Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Fast-Track STTR is to develop a simple, inexpensive, closed-tube PCR method for genotyping and sequence variant scanning. Instead of covalently-labeled probes, one of two primers includes a tail w ith a probe element. After asymmetric PCR, this tail anneals internally to the same strand, snapping back , to form a stem/loop structure. Bot ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Image-Guided Minimally Invasive Robotic Surgery

    SBC: INTUITIVE SURGICAL            Topic: N/A

    DESCRIPTION (provided by applicant): Image-guided surgery allows surgeons to specifically target diseased tissue while sparing healthy tissue, reducing morbidity and improving patient outcomes. Minimally invasive surgical techniques deliver specific intervention without the morbidity associated with large open incisions. Image-guidance technology has the potential to provide significant benefit ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. A Bioactive Prosthetic Vascular Graft

    SBC: BIOSURFACES INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are primarily comprised of polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Unfortunately, these grafts continue to have high failure rates due to secondary complications associated with acute thromboses and incomplete, unregulated cellular prol ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
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