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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Automated preparation of single-cells and nuclei from solid tissues

    SBC: S2 GENOMICS, INC            Topic: 172

    Project Summary AbstractThis project designsdevelopsand automates a novel system to process solid tissue into single cellssingle nucleiand high molecular weight DNA using disposable cartridges without user interventionThe system will support downstream single cell RNA or DNA sequencingsingle nuclei RNA or DNA sequencingand long read sequencers and optical mappingThe long term goal of the project i ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Automated Problem and Allergy Lists Enrichment Based on High Accuracy Information Extraction from the Electronic Health Record

    SBC: Clinacuity, Inc            Topic: NCI

    DESCRIPTION provided by applicant Medical errors are recognized as the cause of numerous deaths and even if some are difficult to avoid many are preventable Computerized physician order entry systems with decision support have been proposed to reduce this risk of medication errors but these systems rely on structured and coded information in the electronic health record EHR Unfortunately ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Automated quantification of lipid droplets in fatty liver tissue sections

    SBC: VALA SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Non-alcoholic fatty liver disease (NAFLD) is emerging as a health crisis and is caused by the accumulation of lipid within liver cells (hepatocytes). The disease is similar to alcoholic liver disease, as lipid droplets (steatosis) appear first, followed by damage to the hepatocytes (steatohepatitis), cell death, inflammation, and cirrhosis. Alarmingly, the inc ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Automated quantification of lipid droplets in fatty liver tissue sections

    SBC: VALA SCIENCES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): NonAlcoholic Fatty liver is associated with obesity, and HCV infection, and is a leading cause of fibrosis, cirrhosis, and liver cancer. Lipid droplet formation (steatosis) is an underlying cause of the pathologies. However, there is considerable variation in the scoring of steatosis and fibrosis by pathologists. This proposal is for Phase II of the STTR projec ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Automated RNA Isolation and RT-PCR for Cancer Detection

    SBC: CEPHEID            Topic: N/A

    DESCRIPTION (provided by applicant): Cepheid develops integrated sample preparation and detection systems for rapid molecular diagnostic applications at a point of use environment. Currently, Cepheid has the GeneXpert system, which is a cartridge and instrument platform for integrated sample preparation and real-time PCR detection of target nucleic acids in biological samples. The current config ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Automated RNA Isolation and RT-PCR for Cancer Detection

    SBC: CEPHEID            Topic: N/A

    DESCRIPTION (provided by applicant): Cepheid develops integrated sample preparation and detection systems for rapid molecular diagnostic applications at a point of use environment. Currently, Cepheid has the GeneXpert system, which is a cartridge and instrument platform for integrated sample preparation and real-time PCR detection of target nucleic acids in biological samples. The current config ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. AutoRegister: A system for enhancing the accuracy of tumor change detection

    SBC: CORTICOMETRICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. AutoRegister: A system for enhancing the accuracy of tumor change detection

    SBC: CORTICOMETRICS LLC            Topic: 102

    PROJECT SUMMARY This project proposes to continue the development of AutoRegisterTMan integrated software based system for enhancing the accuracy of tumor change detectionThe intent of the system is to automate the alignment of a patient s brain scan with that of a prior scan such that subsequent offline tumor measurements do not have error introduced solely by differing slice orientationsWhile si ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. A vaccine against Clostridium difficile infections

    SBC: SORRENTO THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): In this proposal we lay out a comprehensive research plan to evaluate our vaccination strategies targeting Clostridium difficile to prevent or treat infections. With the emergence of highly antibiotic-resistant bacterial strains, new approaches for combating bacterial infections are desperately needed. In this research proposal, Sorrento Therapeutics Inc. (STI ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. A Vaccine for Acute Flaccid Myelitis

    SBC: ALEPH THERAPEUTICS INC            Topic: NIAID

    SUMMARYIn 2014 the United States experienced an outbreak of a previously unknown neurological disease with polio-like symptoms later known as acute flaccid myelitis (AFM). A biennial surge in cases of AFM in 2016 and 2018 has alarmed public health officials. Since then, rapidly accumulating clinical, immunological, and epidemiological evidence has pointed to EV-D68 as the major causative agent of ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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