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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Eye-readable Solution-based Dye Displacement Probe for Large-area Detection of Opioids

    SBC: INTELLIGENT OPTICAL SYSTEMS, INC.            Topic: CBD20AT001

    Intelligent Optical Systems, Inc., in collaboration with Bowling Green State University, proposes to develop a field-rugged, eye-readable indicating spray solution that can immediately detect synthetic opioids over a large area of contamination (i.e., military vehicles, individual protective equipment, clandestine labs, etc.). The proposed chemosensor in a spray solution format will detect multipl ...

    STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense
  2. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: INNOSENSE CORPORATION            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD RESEARCH CORPORATION            Topic: CBD152003

    Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  4. Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring Antibiotics

    SBC: Radiant Genomics, Inc.            Topic: CBD152004

    In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  5. Environmentally Hardened Laser-based micro combat ID

    SBC: Aerius Photonics, LLC.            Topic: SOCOM10008

    Aerius Photonics will address the need for a small, ruggedized, long-range wearable micro combat identification device by developing a compact, portable, battery-powered beacon that employs state-of-the-art mid-wave IR (MWIR), long-wave IR (LWIR) and near IR (NIR) laser technology to emit an eyesafe signal that is easily detected by presently deployed targeting pods. Phase I will demonstrate, eval ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  6. Enhanced Small Arms Ammunition

    SBC: Liquidmetal Technologies, Inc.            Topic: SOCOM06008

    The current materials for small arms ammunitions have several shortcomings, such as environmental concerns, and have difficulty to meet the advancing requirements. The new material solutions and metallurgy is needed to meet the desired performance objectives and as well as safety, legal and environmental rules. The purpose of this Phase-I effort is to develop a bullet design based on a new class o ...

    SBIR Phase I 2007 Department of DefenseSpecial Operations Command
  7. Enhanced Modeling and Simulations of Hypersonics

    SBC: IERUS TECHNOLOGIES INC            Topic: NGA203002

    Endo-atmospheric flight at hypersonic speeds creates an extraordinarily harsh aerothermal environment which may lead to the formation of an ionized plasma layer around some parts of the vehicle. Free electrons in this plasma layer are formed via a combination of collisional ionization and oxidative reactions with carbon products and contaminants. From the perspective of electromagnetic interaction ...

    SBIR Phase I 2021 Department of DefenseNational Geospatial-Intelligence Agency
  8. Enhanced Canine Performance, Protection and Survivability

    SBC: Metro International Biotech, LLC            Topic: SOCOM172002

    Given the benefits of exercise on general health, orally active compounds that can mimic or potentiate the effects of exercise have been of keen interest as therapeutic and dietary ingredients. Our proposed approach for enhancement of USSOCOM Multi-Purpose Canine (MPC) endurance and sensory performance using an exercise mimetic is based on the observation that age-related decline of nicotinamide ...

    SBIR Phase I 2018 Department of DefenseSpecial Operations Command
  9. Embedded Sensor System to Provide Superior Structural Health Monitoring of Fairing Panels

    SBC: ACELLENT TECHNOLOGIES INC            Topic: SOCOM08003

    Swimmer delivery systems, externally mounted on submarines, are subject to hydrodynamic flow and irregular wave-slap loads. These result in unsteady, alternating impacts that can damage exposed surfaces. It is important to track the cumulative stresses imposed on the fairing panels to provide operators with a sense of the remaining service life of the panels. Fairing Panel failure could be catastr ...

    SBIR Phase I 2008 Department of DefenseSpecial Operations Command
  10. Electrostatic, non-fluorescent trigger for aerosolized biological threats using fluctuation enhanced sensing.

    SBC: Orono Spectral Solutions Inc.            Topic: CBD09109

    The objective of this Phase I proposal is to perform a theoretical exploration of the fundamental and practical limits of detection by fluctuation enhanced sensing and statistical inference based sensing methods when applied to an electrostatic-based trigger for non-fluorescent biological warfare threats. To enable < 1000 ACPLA detection levels of bacterial spores in real-time, these statistical ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
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