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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. BioHDF- Open Binary File Standards for Bioinformatics

    SBC: GEOSPIZA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The first wave of Next Generation ( Next Gen ) sequencing technologies combines molecular resolution with extremely high throughput to dramatically reduce sequencing costs and increase assay sensitivity and specificity. These technologies will provide large numbers of laboratories with Genome Center levels of throughput to make discoveries and develop new ass ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Biodegradability and Biocompatibility of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries

    SBC: VenoStent, Inc.            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT Peripheral artery disease (PAD) affects nearly 12 million people in the United States. One of the most common surgical therapies is peripheral artery bypass grafting (PABG). Some patients are eligible for less invasive treatment options like angioplasty, but patients with calcified lesions are not. In patients that do receive PABG, approximately 20% fail within the first y ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Benefit and Safety of Cytisinicline (cytisine) for Cessation of Nicotine E-cigarette Use

    SBC: ACHIEVE LIFE SCIENCES, INC.            Topic: NIDA

    ABSTRACT Nicotine is highly addictive: andgt;95% of unaided attempts at smoking cessation fail by 6 months. Electronic (e)- cigarettes (vaping) are nicotine-delivery devices that may be useful in some individuals for smoking cessation but are not FDA-approved as a smoking cessation aid and long-term use may have uncertain health impacts. Evidence suggests that vaping nicotine may also raise cardio ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  4. Axonal Transport HTS Platform for Neurodegeneration Drug Discovery

    SBC: Bellbrook Labs, LLC            Topic: 106

    DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Automating MRI Delta T1 Methods for the Routine Assessment of Brain Tumor Burden

    SBC: IMAGING BIOMETRICS LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Contrast enhancement on MRI (magnetic resonance imaging) provides the best currently available approach for measuring tumor response to therapy in brain and other solid tumors. Accordingly, criteria have been formulated, by international committees, to guide the assessment of tumor burden by measuring tumor diameters of contrast-enhancing tumor (eg RECIST, Macd ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Automated Support of Robotic Surgical Training, Operations, and Outcomes

    SBC: SPI Surgical, Inc            Topic: A10AT029

    Background: Surgical error reduction requires addressing rapid adoption of new surgical technology. We propose development of a networked surgical assessment platform able to collect performance and outcomes data from multiple surgical platforms and sites for dynamic metrics analysis. Goal: Provide surgical signature ("Surgome") of each surgeon by delivering automated performance feedback to ...

    STTR Phase I 2011 Department of DefenseArmy
  7. Automated Support for the da Vinci Surgical System

    SBC: MIMIC TECHNOLOGIES INC            Topic: A10AT029

    Over 1,400 da Vinci systems are in use worldwide and the install base grows by more than 350 robots each year. While adoption has been rapid, there exists a wide variance in performance of surgical procedures, which has had a negative impact on care quality, cost and patient safety. This is due in part to inefficient training practices and limited mechanisms for objectively assessing surgical p ...

    STTR Phase I 2010 Department of DefenseArmy
  8. Automated Health Assessment through Mobile Sensing and Machine Learning of Daily Activities

    SBC: ADAPTELLIGENCE LLC            Topic: NIBIB

    PROJECT SUMMARY ABSTRACTAdvances in health care have been dramatic since the beginning of the millenniumAs a resultpeople are living longer with age related diseasesand the number of older individuals unable to live independently is rising rapidlyMobile computing offers an unprecedented opportunity to unobtrusively monitor behavior and use the large amount of collected data to automate analysis of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Automated Contingency Management System for Reduction of Alcohol Use

    SBC: Managed Health Connections LLC            Topic: 450

    Project Summary Abstract Alcohol abuse remains a significant cause of preventable morbidity and mortality in the USYet onlyof those with AUD receive treatmentOur groupand others have demonstrated that contingency managementCMis an effective approach for reducing alcohol use in problematic drinkersThis project seeks to demonstrate the capability of an end to end CM platform designed to reduce alcoh ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Autologous HIV-1 resistant T cells through accelerated CCR5 gene disruption

    SBC: PRECISION GENOME ENGINEERING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Treating patients infected with Human Immunodeficiency Virus-1 (HIV-1) is a substantial clinical challenge with evolving pharmaceutical drug and dosing options. Treatments should improve the health and quality of life for HIV-infected individuals by reducing viremia and preserving immunological function. Currents therapeutic approaches utilize combination antir ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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