Award Data

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

On this effort Toyon Research Corp. and The Pennsylvania State University are developing deep learning-based algorithms for object recognition and new class discovery in look-down infrared (IR) imagery. Our approach involves the development of a hybrid classifier that exploits both transfer learning and semi-supervised paradigms in order to maintain good generalization accuracy, especially when li ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

To address the National Geospatial-Intelligence Agency (NGA) need for overhead imagery analysis algorithms that provide uncertaintymeasures for object recognition and aggregation, Intellisense Systems, Inc. (ISS) proposes to develop a new Variational Object Recognition andGrouping Network (VORGNet) system. It is based on the innovation of implementing a Bayesian convolutional neural network (CNN) ...

To address the NGA need for algorithms that fuse observables from over-flight operations and from ground sources to automatically estimatethe degradation of urban environments due to battle damage or natural disasters, Intellisense Systems, Inc. (ISS) proposes to develop a newBayesian Urban Degradation Assessment (BUDA) software system. It is based on the integration of multiple damage assessment ...

The objective of this proposal is to develop instrumentation and algorithms for acquiring facial features for facial recognition in low- and no-light conditions.We will use cross-spectrum matching by exploiting infrared polarimetric imagery which tends to show features that match more closely visible imagery than conventional infrared.In addition to thermal infrared, we will also test subjects in ...

A program to develop a compact, MLA-based, LWIR hyperspectral imager is proposed. The proposed Hyperspectral Chemical Imaging Sensor(HyCIS) builds upon Surface Optics real-time hyperspectral imaging activities, including our 3D full-motion video spectral imaging (FMV-SI)technology and our MIDIS hyperspectral image processor. Simultaneously sampling 16 or more spectral bands from 8 um to 12 um (MWI ...

OKSI will demonstrate autonomous operations concepts for self-guided munition with Fire-Before-Lock-On-Target capabilities and with obstacle avoidance and anti-defilade targets.We will assess the feasibility of implementing the technology in medium caliber munitions.

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

Signature Research, Inc. (SGR) and Michigan Technological University (MTU) propose a Phase I STTR effort to develop a learning algorithm which exploits the spatio-spectral characteristics inherent within IR imagery and motion imagery.Our archive of modelled and labeled data sets will allow our team to thoroughly capture the variable elements that will drive machine learning performance.The overall ...