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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Dielectrophoretic Microfluidic Protein Analysis System

    SBC: Physical Optics Corporation            Topic: CBD09104

    To address the U.S. Army CBD need for a low-cost, universal, robust, and fieldable device for rapid, reproducible identification of protein variants from biological samples with high throughput, Physical Optics Corporation (POC) proposes to develop a new Dielectrophoretic Microfluidic Protein Analysis (DiMiPA) system. The system is based on an electrodeless dielectrophoresis-based, continuous-flow ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  2. Deve;opment of A Handheld Gas Chromatography/Mass Spectrometry

    SBC: FEMTOSCAN CORP.            Topic: N/A

    The ability to develop new technology on the basis of existing commercial technology can offer significant cost savings when compared to research programs to develop new technology from scratch. Continuing developments in mass spectrometry (MS), vacuum Systems and high speed gas chromatography (GC) sampling and analysis methods, have created an opportunity to fully demonstrate a powerful handporta ...

    SBIR Phase I 1998 Department of DefenseOffice for Chemical and Biological Defense
  3. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: ARISAN THERAPEUTICS INC            Topic: CBD192006

    Arenaviruses comprise a diverse group of Old (Africa) and New World (Americas) species. Several species are associated with hemorrhagic fever (HF) with case-fatality rates as high as 30%. Arenaviruses infection typically occurs via the mucosal route through contact with excretions of an infected rodents although direct human-to-human transmission may occur in clinical settings. Lassa arenavirus en ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: ARISAN THERAPEUTICS INC            Topic: CBD192006

    Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of High Performance Water Tolerant Monolythic Scrubber for Closed Circuit Diving Systems

    SBC: Steam Machines, Inc.            Topic: N/A

    Development of a monolythic carbon dioxide scrubber material for us e in closed circuit underwater breathing apparatus. The project will specifically test water tolerance and absorbtion performance in closed breathing loop environments.

    SBIR Phase I 1997 Department of DefenseSpecial Operations Command
  6. Development of enhanced active damping system for the Marine Corps Expeditionary Fighting Vehicle (EFV)

    SBC: MillenWorks            Topic: N04192

    To meet the Marines' need for high speed ship-to-shore and land mobility, the USMC Expeditionary Fighting Vehicle (EFV) is being equipped to provide a leap-ahead improvement over the capabilities of its predecessor, the 30-year old Amphibious Assault Vehicle (AAV). A critical component of improving the EFV's lethality and survivability is to greatly increase speeds across land. While the EFV's t ...

    SBIR Phase I 2005 Department of DefenseSpecial Operations Command
  7. Development of a Non-invasive Negative Ophthalmodynamometer Capable of Measuring Intracranial Pressure in Humans

    SBC: Equinox Ophthalmic, Inc.            Topic: CBD192005

    Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  8. Development of an in vitro assay as correlate of passive immune protection against botulinum neurotoxin to minimize use of whole animal testing

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: CBD11109

    This Small Business Innovation Research Phase I project will develop a non-animal based in-vitro assay for determining the efficacy of Botulinum (BoNT) neutralizing therapeutics; the dual nanopore assay (DNPA). New technologies are currently needed in order to facilitate the development and approval of BoNT vaccines and therapies, and align with the NIH and FDA"s guidance for reducing/replacing th ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  9. Development of an Automated Precision Coating System for SAW-Based Chemical Sensors

    SBC: INTELLIGENT OPTICAL SYSTEMS, INC.            Topic: N/A

    Intelligent Optical Systems (IOS), in collaboration with Tetracore LLC (Rockville, MD), proposes to design, construct, and demonstrate a novel, portable, self-contained, imaging microarray reader (referred to here as Biomapper) to rapidly identify theexposure of Army personnel to biological warfare agents, chemical agents, physical stress, infectious diseases, and other medical conditions that wou ...

    SBIR Phase I 2001 Department of DefenseOffice for Chemical and Biological Defense
  10. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
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