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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Genetic Designs for High-Efficiency Macrolide Production
SBC: FERMALOGIC, INC. Topic: N/AThe macrolides are microbial natural products with many uses in clinical and veterinary medicine. Erythromycin is the best studied example of a macrolide antibiotic; rapamycin and FK506 are promising new immunosuppressant macrolides. The price and availability of macrolides depend on their production efficiency, and therefore, on the genetics of the producing strain. Recently, university studies h ...
SBIR Phase II 1995 Department of Health and Human Services -
Thrombin Peptide Effect of Cellular Antimicrobial Action
SBC: GAL TECH WOUND THERAPIES Topic: N/AN/A
SBIR Phase I 1995 Department of Health and Human Services -
Civamide for The Treatment of Herpes Simplex
SBC: Genderm Corp. Topic: N/AOur long-term objective is the approval of a new drug application (NDA) for civamide as a topical therpes simplex virus (HSV) infections. In the United States, genital HSV affects more than 25 millioHSV effects up to 100 million individuals. The enormous number of affected individuals makes this ancommercial opportunity. In previous preclinical studies using the guinea pig model of HSV-type II inr ...
SBIR Phase I 1995 Department of Health and Human Services -
Development Of An Automated Peptide Synthesizer
SBC: Genosys Biotechnologies, Inc. Topic: N/AThis proposal is directed towards the design, creation, and optimization of a peptide synthesis instrument capable of synthesizing over 100 peptides at a time by using the broadly accepted FMOC or t-BOC chemistries on traditional resin supports. Parallel segmented synthesis will operate at cycle times of 30 minutes for simultaneous addition of 16 amino acids and up to 16 synthesis stacks, and both ...
SBIR Phase II 1995 Department of Health and Human Services -
Extracorporeal Liver Assist Device
SBC: Hepatix, Inc. Topic: N/AOrthotopic liver transplantation is an effective and increasingly popular therapy for a variety of liver diseases, but there is as yet no method for temporarily sustaining a patient awaiting transplant who enters into hepatic failure. C3A is a human liver cell line derived from an hepatoblastoma that retains most of the characteristics of the human hepatocyte. We have cultured these cells in hollo ...
SBIR Phase II 1995 Department of Health and Human Services -
Drug Assocated Polymer Implants for Ocular Indications
SBC: Houston Biotechnology, Inc. Topic: N/AWe will test, in rabbits, implants that slowly release antiproliferative drugs that could improve tocular surgery. In one case the objective is to inhibit the growth of residual lens epithelium aftersurgery, and in another to prevent the sealing up of the drainage pathway by fibroblast activity aftoperation. The primary drug to be tested is Daunomycin, and its carrier will be nylon which has beend ...
SBIR Phase I 1995 Department of Health and Human Services -
Self Administered Metered Dose Liquid Medication System
SBC: J. H. Martin, Inc. Topic: N/AOral pharmaceuticals currently are not delivered in gel form because doses cannot be accurately meapouring a gel into a calibrated cup or a spoon. However, an aerosol dispenser recently invented by tfor this project, Dr. James Martin, appears to offer potential as a means for orally administering iof gel medication. J. H. Martin, Inc., the applicant organization, owns the patent rights to this dit ...
SBIR Phase I 1995 Department of Health and Human Services -
Digital Diary
SBC: Jarrard And Associates Topic: N/AThe Digital Diary is intended to give clinicians administering ambulatory blood pressure or ecg recresearchers evaluating pharmaceuticals and biologicals, a device that will improve subject compliancimprove quality of data collected, and reduce time required to collect and analyze data. The Digitalmicrocomputer controlled, having voice conversion/compression circuitry, and real-time clock/calendav ...
SBIR Phase I 1995 Department of Health and Human Services -
Sparse Random Ultrasound Phased Arrays for Focal Surgery
SBC: Labthermics Technologies, Inc. Topic: N/AA number of studies have suggested that noninvasive surgery using high intensity ultrasound ablatiofeasible, and offers significant advantages over conventional surgical techniques for many applicatiultrasound transducer is used to insonate a small tissue target or targets deep within the body caustargeted tissue. In the past, ultrasound delivery systems for high intensity focal surgical applicate ...
SBIR Phase I 1995 Department of Health and Human Services -
Vectors and Methods for Marker Free Transgenic Plants
SBC: Lakeside Biotechnology, Inc. Topic: N/AWe will develop an optimized transformation system with Agrobacterium to provide marker-free transgGenetically engineered plants that lack antibiotic or herbicide resistance genes are free of concernenvironmental effects that might arise from the use of these marker genes. Moreover, with each new tselectable marker must be used. This proposal will allow development of transgenic plants lacking mav ...
SBIR Phase I 1995 Department of Health and Human Services