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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Insulin Pathway Agonist for Alzheimer's Disease

    SBC: MEDCHEM PARTNERS LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Even though the association of -amyloid peptide (A ) deposition and Alzheimer's Disease (AD) underpins the major hypothesis for disease progression and possibly causation and several drugs addressing the formation or removal of -amyloid plaques have entered clinical trials, no effective therapy exists to date for AD. This reality calls for new targets th ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Testing the feasibility of Rendever with older adults with cognitive impairments and their adult children.

    SBC: RENDEVER, INC.            Topic: NIA

    Alzheimer s disease affects approximatelymillion AmericansNIAand bythis number is expected to more than double tomillionUntil cures for the dementias are discoverednew technologies are imperative that can help reduce the emotional burden of AD ADRD for older adults and their care giversGoal C of NIA s strategic planIn this STTRSmall Business Technology TransferPhase I studywe test the feasibility ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Optimizing Usability of the Orally Rehydrate Children at Home Mobile Application- Optimize ORCAH

    SBC: Data2Care Technologies, LLC            Topic: NICHD

    Project Summary Abstract Acute gastroenteritisAGEinfectious diarrhea is a common condition that is costly in the US and highmortality in developing nationsThe cornerstone of AGE management is oral rehydration therapyORTan evidence based technique that has saved overmillion lives in theyears since its introductionThe problem we aim to address is ORT s underuse in developed countries specifically in ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Non-Opiate Topical Formulations for Treating Pain Associated with Molar Extractions

    SBC: ARCATO LABORATORIES, INC.            Topic: NIDCR

    Project Summary Abstract Most of the deaths from drug overdoses are driven by synthetic opioidsDentistry highly contributes to the opiate addiction epidemicFollowing dental surgeryof oral surgeons prescribe opiatesand most opiates are prescribed after wisdom teeth extractionthird molarto reduce pain caused by dry socketsApproximatelymillion surgical tooth extractions are performed onmillion patien ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Targeted Polymer Micelles for Treatment of Metastatic Melanoma

    SBC: INTEZYNE TECHNOLOGIES, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): According to the American Cancer Society, half of all men and one-third of all women in the United States will develop cancer in their lifetime. While chemotherapy has dramatically improved the survival rate of cancer patients, it comes at the cost of severe toxicities and in some cases poor response rates. In order to address these shortcomings, equal investme ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Novel Home-Based and Low-Cost ECG Device for periodic evaluation of the presence of atrial fibrillation

    SBC: Global Instrumentation, LLC            Topic: 600

    Abstract Atrial fibrillationAFprevalence is estimated toof the general population in the United StatesA shockingtoaccording to studiesof patients with AF are unaware of their diagnosissilent AFMost AF patients will suffer from congestive heart failure or and develop thromboembolic events leading to a dramatic reduction of patientsquality of lifeand a significant consumption of health care resource ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Commercial Polymerases to Create Receptors, Ligands, and Catalysts on Demand

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: NIGMS

    Commercial Polymerases to Create Receptors Ligands and Catalysts on Demand Firebird Biomolecular Sciences LLC University of Texas Steven A Benner Andrew D Ellington ABSTRACT Innovators at Firebird Biomolecular Sciences LLC have created several generations of an artificially ex panded genetic information system AEGIS that adds eight nucleobases that form four additional pairs Z P S ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Sensor Network for Monitoring Real-world Arm Activity of Rehabilitation Patients

    SBC: ACTIVE WAVE, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): Evidence and theory indicate that laboratory measures of impairment and function do not predict how older adults actually function in daily life. Thomas Glass (1998), for example, reports marked differences between functional activities that community residents can do and do do in survey data from the MacArthur Studies of Successful Aging. Therefore, subst ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Numerical Tools for Predicting Drug Dissolution Profiles

    SBC: RES Group, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): This STTR Phase I proposal describes the development of a modeling framework that combines a mesoscopic model for hydrodynamics with dissolution kinetic models in order to accurately describe the dissolution behavior of drugs. The complexities of the drug dissolution problem have led to the development of empirical methodologies being the widespread practice in ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Quit IT: Development of a Web-based 3D Coping Skills Game to Increase Self-Effic

    SBC: Muzzy Lane Software            Topic: NIDA

    DESCRIPTION (provided by applicant): Tobacco use remains the single most preventable cause of premature deaths and cancer.1 Building on more than a decade of clinical and research experience in treating tobacco-dependence, we propose to address this problem with a new academic-small computer game business partnership that will develop a novel e-health tobacco cessation and relapse prevention produ ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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