Award Data

DESCRIPTION (provided by applicant): Phase I funding for this project supported the successful development of the backbone for a new generation of retroviral gene therapy vectors that contain safety and efficacy features designed to overcome the problems that have been found with retroviral vectors used in current clinical trials. The model disease targeted is the well-studied genetic disease Aden ...

In recent years, the expanding in-space servicing, assembly, and manufacturing (ISAM) market has generated a growing demand for reliable and scalable robotic capture mechanisms. Apart from a few exceptions, such as remote survey and remote recharge, all s

Project Summary Genetic and pathologic evidence in andapos;pureandapos; tauopathies such as Progressive Supranuclear Palsy (PSP), Corticobasilar Degeneration (CBD) and some cases of Fronto-temporal Dementia (FTD) directly implicate tau as causing neuronal cell death, while in Alzheimer’s Disease (AD) tau accumulation correlates with development and progression of cognitive impairment. Because of ...

SensorMetrix proposes to develop innovative self-healing polymers for integration into fibrous composites and adhesive joints. These polymers heal damage in the form of cracks (macro- through nanoscale) at the molecular level through a novel reversible covalent bond. Polymer composites are notorious for their tendency to microcrack in the matrix regions due to thermal cycling , fatigue loading a ...

Glider, Logistics, STOM

We propose to mature LG-X glider technology by manufacturing full-scaled prototypes and characterizing them in land-based flight-testing by using commercial aircraft to drop the gliders. Validated components such as the landing parachute, folding wing mechanism, and autopilot control system will undergo integrated flight-testing. Logistic Gliders will provide a considerable cost share to support ...

In order to counter emerging threats from the Middle East and Southeast Asia, the Ballistic Missile Defense System (BMDS) is acquiring new sensor (e.g. AN/TPY-2 and PTSS) and weapon technology (SM-3). As these new technologies becomes fielded, the BMDS's Command, Control Battle Management and Communication (C2BMC) component must be able to correlate objects between multiple sensors. Inheren ...

In order to counter emerging threats from the Middle East and Southeast Asia, the Ballistic Missile Defense System (BMDS) is acquiring new sensor (e.g. AN/TPY-2 and PTSS type) and weapon technology (SM-3). As these new technologies are fielded, the BMDS's Command, Control, Battle Management and Communication (C2BMC) component must be able to correlate objects between multiple sensors. Inher ...

75748-Cathodes have a dominant influence on the quality of the electron beams produced from laser photo-cathodes in radio frequency (rf) guns used as injectors in many electron accelerators. Similar limitations are also suffered by thermionic cathodes in diode guns used in high-power rf amplifiers for accelerator applications. These limitations could be surmounted by a field-emission cold cathod ...

In this Phase I Project ACTA and its partners will demonstrate the feasibility of developing a risk-based mission path planning (RB MPP) approach. Areas of interest to the Navy where a RB MPP address critical needs include enabling less restrictive UAS operations within the US National and Foreign Airspaces. The Phase I will demonstrate feasibility with a two-step approach. The first step will dem ...