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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
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SBC: BIOMARCK PHARMACEUTICALS, LTD Topic: NEI
ABSTRACT Uveitisthe most common form of intraocular inflammationaccounts forof preventable blindness in the USTreatment options are limited to cortiscosteroids and or immunosuppressantsbut both of these therapies show limited efficacy and are associated with numerous adverse and potentially serious side effectsNew therapeutic targets leading to effective and safe treatments are urgently requiredA ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: MYOFINITY BIOSCIENCES INC Topic: NIAMS
PROJECT ABSTRACT The long term goal of this project is to optimize a protein therapeutic for Duchenne muscular dystrophyDMDand potentially other muscle diseasesthat will enhance the repair capacity of muscle cell membranes that are compromised by mutations in the dystrophin dystroglycan complexMutations in the dystrophin dystroglycan complex result in Duchenne muscular dystrophyMyos Incis developi ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: KLEIN BUENDEL, INC. Topic: 102
Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: SANERON CCEL THERAPEUTICS, INC. Topic: 999
ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Development and evaluation of diffuse correlation spectroscopy to monitor cerebral blood flow and detect intraventricular hemorrhage in extremely premature infantsSBC: 149 MEDICAL INC Topic: 103
PROJECT SUMMARY ABSTRACT Every year in the United States aboutof theinfants born extremely prematureandltweeks gestational age and andltg birth weightELGAdevelop intraventricular hemorrhageIVHIVH is associated with high risk for cerebral palsy and significant intellectual disabilitycausing lifelong implications for affected children and their families and considerable economic burdenIVH is caused ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Z-Quick, LLC Topic: NIAID
Project Summary Abstract The advent of the Zika virusZIKVepidemic around the world has and will cause problems for the correct diagnosis of flavivirus infectionsFor many yearsDENV serological diagnosis was relatively straightforwardHoweverafter the recent ZIKV epidemiccross reactive antibodiesAbsgenerated after ZIKV infection will bind to DENV even if the patient has never had DENVThe only FDA app ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: CORTICOMETRICS LLC Topic: NIA
Project Summary Normal human neuroanatomy is incredibly variableand increases with ageThis impedes the ability of neuroimaging to detect effects in neurological conditions such as Alzheimerandapos s diseaseADHuntingtonandapos s diseaseHDmultiple sclerosisMSand schizophreniaMost of the recently available state of the art quantitative imaging tools still use cross sectional methods to analyze repeat ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: VOX BIOMEDICAL LLC Topic: NIDA
Project Summary This proposal seeks to expand upon breath analysis technology that is being actively studied as the focus of NIH grant #6R42DA049655-02 and leverage this technology for rapid COVID-19 diagnostics. There is a dire need for sensitive and specific diagnostic tests for COVID-19 that can be performed quickly. The differential mobility spectrometry (DMS) breath analysis technology curren ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: APTIMA INC Topic: DHA18B001
Current cervical spine assessment methodologies are focused on subjective measures (i.e. pain reports) and range-of-motion (ROM) measures that only measure maximum head excursion and reach, but not dynamic motion. Due to report bias and existing incentiveSTTR Phase I 2019 Department of DefenseDefense Health Agency
SBC: SWITCHBOX INC Topic: DHA18B001
Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck heSTTR Phase I 2019 Department of DefenseDefense Health Agency