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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of Tumor Proliferation PET Tracer FLT using a Low Cost Single Dose Automatic Production and Quality Control Biomarker Generator System

    SBC: ABT Molecular Imaging            Topic: 102

    DESCRIPTION provided by applicant Worldwide a person dies from cancer every seconds Positron emission tomography PET is an effective tool that is critical in diagnosing cancer and monitoring treatment efficacy PET imaging relies on use of short lived radioisotopes Commercial distribution of the most commonly used radio tracer F FDG has resulted in patient population coverage in ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. BMX-001 as a Therapeutic Agent for Treatment of High-Grade Gliomas

    SBC: BIOMIMETIX JV LLC            Topic: NCI

    DESCRIPTION provided by applicant Phase and Phase clinical trials of a new class of redox active pharmaceutical are proposed in high grade glioma WHO grade III and IV This project will test a compound that crosses the blood brain barrier and which prevents hippocampal stem cell loss and white matter degradation following radiation therapy RT The compound also inhibits tumor regrowth f ...

    SBIR Phase II 2015 Department of Health and Human Services
  3. Beam Control with a Broadband, High Speed X-Y Variable Light Modulator

    SBC: Boulder Nonlinear Systems, Inc.            Topic: 400

    DESCRIPTION provided by applicant The primary proposed objective is to realize a broadband high speed spatial light modulator SLM for microscopy applications Current microscopy techniques frequently employ spatial light modulators to manipulate the phase and amplitude of light illuminating a sample or and or transmitted by a sample The phase and amplitude of light in the microscope illumina ...

    SBIR Phase II 2015 Department of Health and Human Services
  4. Personal Exposure Monitoring of the Air Pollutants as a K-12 Educational Tool

    SBC: 2B TECHNOLOGIES, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant Personal Exposure Monitoring of Air Pollutants as an Educational Tool in the GO Treks project launched by the Phase I grant students at schools throughout the U S used personal monitors to measure the air pollutants black carbon and ozone along treks of their own design The treks were uploaded to blogs in the GO website where they were displ ...

    SBIR Phase II 2015 Department of Health and Human Services
  5. Expressing bacterial bioluminescence in human cell lines: Engineering autobioluminescent reporter cells to screen for endocrine disruptor chemicals

    SBC: 490 BIOTECH INC            Topic: NIEHS

    DESCRIPTION provided by applicant Expressing bacterial bioluminescence in human cell lines Engineering autobioluminescent reporter cells to screen for endocrine disruptor chemicals Project Summary This Small Business Innovation Research Phase II project proposes to build upon our successful Phase I demonstration of autonomous endocrine disruptor chemical EDC detection using human cell lines ...

    SBIR Phase II 2015 Department of Health and Human Services
  6. Micro Patterned Intraocular Lens Membrane for Reducing Incidence of PCO

    SBC: Sharklet Technologies Inc.            Topic: N

    DESCRIPTION provided by applicant The exponential increase of diabetics and the elderly in the U S has more than tripled the number of cataract surgeries performed in just two decades As many as half of these surgeries will lead to posterior capsular opacification PCO which requires follow up Nd YAG laser capsulotomy surgery Without this additional procedure patients can suffer permanent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Migrate enzyme modeling technology from development site to experimental research

    SBC: Stewart, James            Topic: 300

    Project Summary Abstract The rate of progress in developing new pharmaceuticals could be accelerated if experimental researchers had practical methods for modeling enzyme mechanisms Unfortunately all current programs have severe limitations either being too slow too complicated or too inaccurate Although an efficient and accurate method for modeling mechanisms in enzyme catalyzed reactions ...

    SBIR Phase II 2015 Department of Health and Human Services
  8. A Holographic Module for Multiphoton Microscopes in Neuroscience

    SBC: Boulder Nonlinear Systems, Inc.            Topic: 101

    DESCRIPTION provided by applicant Improving our understanding of the functional circuitry of the brain has important and manifold implications for our understanding of mental health as well as fields like consciousness and computing In the last decade optical techniques have arisen that allow both recording and control of targeted neurons for brain mapping and many of the best of these tech ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Location-based Smartphone Technology to Guide College Students??? Healthy Choices Phase II

    SBC: KLEIN BUENDEL, INC            Topic: NCCDPHP

    DESCRIPTION provided by applicant Poor eating habits sedentary behavior and deficient sleep quality are problematic for many college students Surrounded by numerous unhealthy food choices and physical activity barriers students are vulnerable to overweight and chronic diseases such as diabetes heart disease and cancer Todayandapos s college students are more technologically connected tha ...

    SBIR Phase II 2015 Department of Health and Human Services
  10. Photochemical ClO2 Decontaminant for Biological Agent Neutralization

    SBC: TDA Research, Inc.            Topic: HSB0142001

    DHS requires the ability to respond to an attack with biological agents. Specifically, it requires a decontaminant to kill anthrax spores on building exteriors and interiors, and even large outdoor areas. In this proposal we describe an innovative bio-agent decon technology that is particularly suitable for decon over wide areas; and as far as we are aware, no other technology in development can ...

    SBIR Phase II 2015 Department of Homeland Security

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