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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor
SBC: SFC FLUIDICS, INC. Topic: 200Development of a Low Profile Dual Hormone Patch Pumpwith Novel Occlusion Sensor Project SummaryThe Specific Aim of this project is to develop a discretelow profiledual hormone drug delivery system using SFC Fluidicsenabling microfluidic technologiesA DualPumpwill be developed in which one proprietary ePumpbody will independently and accurately deliver both insulin and glucagon from two separate re ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Multicolor Photoacoustic Malaria Detector
SBC: CytoAstra, LLC Topic: NIAIDSummary Malaria continues to be a global health prioritywith almost half of the world s populationbillionat risk and arounddeaths each yearOvertreatment is caused by lack of diagnosis and contributes to resistancea huge threat as illustrated by artemisinin resistance in Southeast AsiaLittle progress has been made in the novel methods to diagnose malarialet alone in reliably identifying asymptomati ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
DMSO-free Cryopreservation of Bone Marrow-derived Stem Cells
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NHLBIABSTRACT Stem cell transplantation in the form of bone marrowperipheral blood or cord blood derived cells is commonly performed for reconstitution of the hematopoietic system of patients suffering from cancers and non malignant diseasesCurrent practice for cryopreservation of hematopoietic and mesenchymal stem cells is to employ the cell permeating cryoprotectant dimethylsulfoxideoften with an add ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Automation of bioengineered epithelial construct cryopreservation
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NIBIBABSTRACT BSTRACT In an effort to reduce the use of animals for toxicity testingcompanies have developed bioengineered in vitro skin models to replace the Draize skin irritation testThe development of tissue models has been further pushed by the European Union that prohibited the use of animals infor collecting toxicological data on cosmetic ingredientsSupply of bioengineered tissues is a significa ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Therapeutic Inhibition of MIF to Improve Glucocorticoid Response
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDAbstract Despite the advent of biological therapiesglucocorticoidsGCsremain the most widely prescribed medicines for the management of inflammatory diseases such as lupusasthmamultiple sclerosisand rheumatoid arthritisHoweverlong term and high dose GC use is inevitably accompanied by systemic toxicityThere are no adjunctive therapies that could enhance the disease modifying effects of GCs at low d ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Therapeutic Inhibition of BCL6 in Systemic Lupus Erythematosus
SBC: L2 DIAGNOSTICS LLC Topic: NIAMSABSTRACT Systemic autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus are characterized by polyclonal T cell activation driving the production of pathogenic class switched autoantibodiesThe class switchedsomatically mutated antibodies are generated from germinal centerGCB cellsA subset of effector CDT cellsknown as T follicular helperTfhcellshas been shown to play an ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
eCPAT: Advancing public park information and technology resources to diverse audiences for healthy communities
SBC: EnQ LLC Topic: NCIProject Summary Abstract Quality parks provide numerous benefits to individuals and communitiesincluding health cost savings through physical activity and stress reliefincreased tax revenue via augmented property values and attracting businessesand positive social and environmental impacts through outcomes such as civic pride and pollution controlThe Community Park Audit ToolCPATprovides a compreh ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of TP-252 for the Maintenance of Remission in Pediatric Ulcerative Colitis Patients
SBC: Thetis Pharmaceuticals LLC Topic: 300ABSTRACTUlcerative colitisUCis a chronicrelapsing form of Inflammatory Bowel DiseaseIBDcharacterized by inflammation and ulceration of the colon and rectumUncontrolled UC can lead to serious complicationsincluding toxic megacolon and colorectal cancerThe disease affects approximatelypeople in the USwith up toof patients diagnosed before ageYoung UC patients typically present with more severe sympt ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Administrative Supplement to Promote Diversity in Research and Development Small Businesses
SBC: NEUROENE THERAPEUTICS INC Topic: NINDSAbstract Neuroene Therapeutics is a biotech company established to develop and commercialize safe effective therapies for epilepsyinpeople develop epilepsy in their lifetimehowever the currently available anti epileptic drugsAEDshave several issues and liabilities that leave unmet market needssuch asnot controlling seizures forof patients with epilepsycurrent AEDs only treat the symptoms of epilep ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a Point of Care Diagnostic Screening test for Kawasaki disease
SBC: L2 DIAGNOSTICS LLC Topic: NICHDABSTRACT Kawasaki DiseaseKDis a febrile childhood vasculitis with potentially catastrophic clinical outcomesUntreatedone in five children develop coronary artery aneurysms causing significant morbidity and mortalityTypical KD presents as a febrile illness andgtdays in children andltyears oldThere are no diagnostic tests for KDit is diagnosed clinically based on a fever andgtdays with at leastofphy ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health