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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 31 - 40 of 207728 results
  1. Home Monitoring of Metabolic Disorders

    SBC: SEQUITUR HEALTH CORP            Topic: NICHD

    PROJECT SUMMARY This proposal is submitted in direct response to NOT-HD-22-009 Notice of Special Interest (NOSI): Innovative Technologies to Improve Assessments, Interventions, and Outcomes for Individuals with Intellectual and Developmental Disabilities [IDD] (R43/R44). Persons of all ages with certain metabolic disorders are at-risk for metabolic crises when a certain metabolite accumulates, whi ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Development and clinical assessment of a robust, 3D printed titanium, myoelectric powered prosthetic digit system

    SBC: POINT DESIGNS, LLC            Topic: 106

    ABSTRACT Approximately 600,000 people live with partial hand amputations in the United States, with an estimated 14,500 new cases occurring each year. Despite the advances in miniaturized electronics and motors, there has been very little advancement in mechatronic prosthetic digits for this underserved patient population. In fact, to date, there is only one myoelectric prosthetic option for patie ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Blood-based Test for Identifying Synucleinopathy in Patients with Dementia

    SBC: Neurodex Inc            Topic: NINDS

    PROJECT SUMMARY In this Fast Track SBIR application, NeuroDex, Inc. proposes to use its expertise in extracellular vesicle (EV) immunoaffinity isolation to develop a blood test that detects synucleinopathies with high sensitivity, with the long- term goal of helping clinicians identify patients for whom antipsychotic drugs are harmful and contraindicated. Development and commercialization of a sen ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Hybrid ELISA: Simple and specific one-tier assay for Lyme disease

    SBC: KEPHERA DIAGNOSTICS LLC            Topic: NIAID

    Abstract Lyme disease, caused by infection with the spirochete Borrelia burgdorferi or closely related species, is the most common vector-borne disease in the United States, accounting for nearly 500,000 infections per year according to recent public health estimates. It is also one of the few infectious diseases that requires a two-step laboratory testing protocol, comprising a screening assay, t ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. System for Volumetric 2-photon Imaging of Neuroactivity Using Light Beads Microscopy

    SBC: MICROBRIGHTFIELD, LLC            Topic: 101

    Abstract This project aims to develop and commercialize the Volumetric Calcium Imaging 2-Photon Activity Microscope, vCAm™, a revolutionary new 2-photon microscope based on a technological breakthrough called Light Beads Microscopy (LBM) that was recently developed by Dr. Alipasha Vaziri and co-workers (Lab. Neurotechnol. Biophys., Rockefeller Univ., New York, NY). The game-changing innovation i ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Dual-Targeting ClpP Activating Antibiotic

    SBC: ARIETIS CORPORATION            Topic: NIAID

    The World Health Organization has declared that antimicrobial resistance is one of the biggest threats to global health. It was estimated that by 2050, deaths due to drug resistant bacteria will exceed those caused by cancer. The goal of this project is to develop a new ureadepsipeptide antibiotic (UDEP) to treat infections caused by Gram-positive pathogens, such as bacteremia, pneumonia, endocard ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a regional anesthesia guidance system to increase patient access to opioid-sparing analgesia for hip fracture pain

    SBC: RIVANNA MEDICAL, INC.            Topic: NIAMS

    PROJECT SUMMARY/ABSTRACT For the rt330,000 Americans that are hospitalized for hip fractures yearly, rapid treatment of pain and surgical intervention is critical to recover mobility and reduce the risk of death. Parenteral opioids are the standard of care to manage acute hip fracture pain but increase the risk of adverse events and outcomes, including delirium and recurrent opioid use. Ultrasound ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. IND-enabling Preclinical Development of a Sustained-release Pritelivir Intravaginal ring for the Treatment and Prophylaxis of Genital Herpes

    SBC: AURITEC PHARMACEUTICALS, INC.            Topic: NIAID

    SUMMARY The broad, long-term goal of this project is to develop a pritelivir intravaginal ring (IVR) for the treatment and pre-exposure prophylaxis of genital herpes, a common problem that affects more than 30 million Americans. Recurrences are common and may be painful, and infection is life-long, yet few treatment options exist. Pritelivir is a promising α-helicase inhibitor that has been prove ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. SAGE LEAF 2: An Online Self-Guided Positive Emotion Regulation Program to Reduce Alzheimer's Dementia Caregiver Burden Delivered through Caregiver-Serving Organizations

    SBC: BRIGHTOUTCOME INC.            Topic: NIA

    Project Summary In the US alone, more than 11 million family caregivers provide care for someone with Alzheimer's disease or other dementia on a daily basis.1 These family caregivers have been estimated to shoulder 70% of the total cost of care over their care recipient’s lifetime, costs which include medical bills and unpaid caregiving hours.2 Caregiving-related stress contributes to social iso ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Eliminating Ventricular Tachycardia: Pivotal Clinical Trial using the Durablate® Catheter

    SBC: Thermedical Inc.            Topic: NHLBI

    Ventricular tachycardia (VT) causes more than half of the 170,000–450,000 sudden cardiac deaths (SCD) that occur annually in the United States. Implantable cardioverter defibrillators (ICDs) are the standard of care, but they are expensive (the total cost of an ICD implant exceeds $50,000) and not curative. Patients who receive ICDs are subject to shocks to halt episodes of VT, and those shocks ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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