Award Data

DESCRIPTION provided by applicant Problem to be Solved Cystic fibrosis CF is a global health issue that affects over people worldwide including Americans Lung disease is the primary cause of morbidity and mortality in CF patients and is characterized by intense inflammatory responses in the airways The Product and Long Term Goal Nanometics LLC dba PHD Biosciences PHD ...

DESCRIPTION (provided by applicant): Nuclear accidents and terrorism present a serious threat for causing mass-casualty scenarios. In radiation events, many people receive non-uniform whole-body or partial-body irradiation. The risk of exposure to ionizingradiation due to terrorist activities could result in acute injury as well as long-term adverse health effects in thousands of people. The lung ...

DESCRIPTION provided by applicant Assessment of chemicalsandapos potential to cause chromosomal damage is an established and important part of preclinical genotoxicity safety testing for many consumer products industrial chemicals and all pharmaceutical agents Currently the mammalian erythrocyte micronucleus test is the most commonly employed assay for in vivo assessment of chromosomal damage but ...

For 50 years Babington has pioneered the field of ultra-clean combustion for home and off-grid heating and cooking. Our unique air-atomization and burner technology provides for near perfect combustion of liquid fuels with variable heat outputs. Babington burners have heated homes and millions of meals for U.S. militaries and disaster relief organizations worldwide. Recently, we reengineered ou ...

DESCRIPTION (provided by applicant): It is well recognized that current batteries of genetic toxicology assays exhibit relatively high sensitivity, meaning they effectively identify genotoxic carcinogens. However, a critical deficiency with current approaches exists-namely, the specificity of the in vitro mammalian cell genotoxicity tests is low, as they yield a high incidenc of positive results t ...

DESCRIPTION (provided by applicant): This Phase I SBIR application is submitted in response to the call by DHHS for new tests for qualitative measurement of HCV RNA for diagnosis of chronic HCV infection in patients. The need is for HCV RNA assays that areas reliable but less expensive and resource-demanding than current molecular assays. The new test proposed for research and development consists ...

DESCRIPTION (provided by applicant): Cigarette smoking remains the number one cause of preventable morbidity and mortality in the U.S. Each year, one third to one half of smokers attempt to quit at least once; however, approximately 94% of quit attempts fail. A number of interventions have been developed to help smokers initiate and maintain abstinence. Unfortunately, even though most smokers expr ...

By the time an individual is diagnosed with Alzheimer s Disease AD or dementia they have often already experienced both gradual and dramatic changes to their health cognitive function employment and financial status among other life events A number of key interview based studies like The National Health and Aging Trends Study NHATS and The Health and Retirement Study HRS have provided u ...

PAR-11-133 - PI, Gretchen L. Snyder, PhD Casein Kinase I Inhibitors for Autism Project Summary/Abstract Autism is a neurodevelopmental disorder characterized by abnormal social interaction, deficits in interpersonal communication, and repetitive stereotyped behaviors with a number of individually- occurring associated symptoms, including intellectual impairment, anxiety, seizures, hyperactivity, h ...

DESCRIPTION (provided by applicant): The goal of this research is to develop a new approach to bring diagnosis and monitoring tests for HIV to the primary care level (primary care provider office, small healthcare clinics and labs, and community health center labs) by introducing a multi-functional cell analysis and immunoassay platform that is portable, low cost and easy to use. It will allow pat ...