Award Data

To address the OSDs need for a network defense technology based upon dynamic adaptation of a network or an intruders perception of it, Physical Optics Corporation (POC) proposes a new Fast Network Information Scrambling Technology (FIST). FIST is based on an innovative low-complexity network information scrambler algorithm implemented on low-cost small-scale commercial off-the-shelf hardware compo ...

In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

The fundamental problem addressed by this SBIR proposal is the capability to uncover new entity types, relations and topics that are implicit in text documents.Joint inference offers an opportunity to make discoveries that are more accurate and more nuanced than traditional pipelined approaches, but the hypothesis space is more complex and extraordinarily large.In this project we propose to develo ...

Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

Metronome Software develops a Domain Encryption (DomCrypt) system for securing Android-based Commercial Off The Shield (COTS) mobile devices. DomCrypt software suite, through its creation of separate DomCrypt-encrypted domains, provides the warfighters the means for accessing and dynamically sharing data in a variety of formats using COTS mobile devices. Metronome also employs a strong-security fo ...

Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometric measurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed software app aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D im ...

Alphavirus infection, which may cause encephalitis and death, are recognized as potential biological warfare agents. There are no approved medical countermeasures against diseases caused by Alphaviruses. In this project, thermostable single domain antibodies capable of crossing the blood brain barrier (BBB) and neutralizing encephalitic viruses will be developed using Abzymes proprietary in vivo S ...

To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...

Some of our nations adversaries possess advanced technologies and equipment necessary for the processing and development of Weapons of Mass Destruction (WMD). There is a growing risk that these capabilities and technologies will be used against the United States or our allies. For this reason, an opportunity exists to develop offensive solutions that will enable warfighters to combat WMD at the so ...

As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as a fa ...