Award Data

In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...

As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as a fa ...

Electron spin resonance (ESR) spectroscopy is a widely used forensic technique to study post-nuclear debris fields, radiation-induced damage in solids and many other phenomena surrounding the interaction of radioactivity with solid matter. ESR spectroscopy is also used to analyze dust, smoke and other gaseous samples. Our Micro-ESR technology has the benefit of being an extremely robust, lightweig ...

This program develops innovative technology for chip-to-chip and intra-chip interconnects that will operate in extreme radiation environments.There is considerable development in chip-to-chip and intra-chip interconnects in the commercial market.This program will leverage these advancements and demonstrate their applicability to satellite and unmanned avionic vehicles (UAV) platforms.

The fundamental problem addressed by this SBIR proposal is the capability to uncover new entity types, relations and topics that are implicit in text documents.Joint inference offers an opportunity to make discoveries that are more accurate and more nuanced than traditional pipelined approaches, but the hypothesis space is more complex and extraordinarily large.In this project we propose to develo ...

To address the DTRA need to enhance island-mode tactics for defense critical infrastructure (DCI) in the event of commercial power grid loss disruption due to an electromagnetic pulse (EMP) or high power microwaves (HPMs), Physical Optics Corporation (POC) proposes to develop an Optimizing power Availability and Sustainability in Islanded Sites (OASIS) strategy based on islanded power management, ...

Rock West Solutions' Phase 1 objective is to design, model, and report performance on a radiation spectrometer for use in drive by, low signal count, applications.We will design a custom sensor for DTRA's unique mission and apply our Sparse Signature Identification algorithm to provide isotope identification with confidence assessment for DTRA's mission.

To address the OSDs need for a network defense technology based upon dynamic adaptation of a network or an intruders perception of it, Physical Optics Corporation (POC) proposes a new Fast Network Information Scrambling Technology (FIST). FIST is based on an innovative low-complexity network information scrambler algorithm implemented on low-cost small-scale commercial off-the-shelf hardware compo ...