Award Data

Genben Lifesciences dba GB HealthWatch is a digital health and nutritional genomics company Our mission is to help fight common diet and lifestyle related chronic diseases with precision nutrition and advanced mobile technologies Our company developed the HealthWatch mobile app for tracking dietary intake physical activity and health related symptoms This mobile app has received excell ...

SMALL MOLECULE THERAPEUTICS FOR ALZHEIMERandapos S DISEASE SUMMARY Alzheimerandapos s disease AD is a progressive and fatal neurological disorder that affects approximately one tenth of the population over the age of There is currently no cure for the disease The pathological hallmarks of the disease include the formation and accumulation in the brain of amyloid A Earlier therapeut ...

Project Summary Abstract Abilita Bio AB an innovation driven biotechnology company requests SBIR Phase I funding for the discovery of novel therapeutic antibodies targeting G protein coupled receptors GPCRs for the treatment of metastatic breast cancer In cancer therapy each treatment modality has its own limitations Clinical studies clearly indicate that immunotherapy with checkpoint inhi ...

PROJECT SUMMARY The broad long term goal of this project is to develop a low cost miniature fully implantable wireless glucose sensor that is easy to implant and extract and can empower diabetic patients type I and type II manage their disease in a seamless manner Diabetes affects more than million people worldwide with an estimated increase of about million by the year Therefor ...

DESCRIPTION provided by applicant The anemia of chronic disease ACD anemia of inflammation is commonly observed in chronic inflammatory states and may hinder patient recovery and survival Induction of hepcidin mediated by IL leads to iron limited erythropoiesis and anemia Gardenghi Iron homeostasis reviewed by Ganz depends on regulated absorption and transport of dietar ...

Abstract Brain swelling is a serious complication of multiple disease conditions including liver failure metastatic tumors traumatic brain injury and ischemic stroke TBI and stroke afflict M and K persons per year in the US alone and is a costly health care burden and a devastating social burden Current treatments for brain swelling are limited and generally ineffective highligh ...

Abstract Summary million Americans and billion people worldwide are obese or overweight this is a major health concern associated with heart disease cancer and diabetes Obesity has proven difficult to treat but engineered microbes show promise E coli engineered to produce N acyl phosphatidylethanolamines NAPEs resulted increased satiety decreased food intake decreased body fat ...

Project Summary Linking infectious agent diagnostics to clinical decision making at the point of care requires a fast highly sensitive and simple to use method that takes into account the infrastructure and workflow in clinical settings of both developing and developed regions In addition being able to distinguish among multiple potential infectious pathogens in a single test is of great impor ...

DESCRIPTION provided by applicant The abuse of illicit drugs such as cocaine marijuana and heroin remains a critical public health concern throughout the country and is associated with staggering economic and social consequences Cocaine remains the most frequently recorded illicit drug in emergency hospital visits and the leading cause of drug related deaths in the United States Since as hi ...

PROJECT SUMMARY The goal of the current project is to elaborate upon reconstruct and advance to pivotal trial readiness a multimodal closed loop assessment to treatment mobile application for individuals with mood disorders Major Depressive Disorder MDD is a recurrent and disabling condition and a leading cause of global disease burden Nearly half of the patients fail to respond to psycho ...