Award Data

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

The broader impact/commercial potential of this project lies in next generation gas turbines where the heart of the engine, the combustor and the blade, are constructed from ceramic matrix composites (CMCs). These developments will spell a new phase of air transportation beyond the current engines that rely upon nickel-base superalloys, which have reached their maximum capability. The ceramic engi ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to bring modern data analytics to the book publishing industry and apply machine learning to extract and articulate human emotion as applied to the reading of literature for the first time in history. This innovation will dramatically change the way books are discovered, resulting in t ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will provide the market with a novel non-invasive method for measuring fluid status in patients with congestive heart failure (CHF). The ability to detect volume status changes prior to the onset of heart failure symptoms has tremendous patient care and economic impact. According to the Americ ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be the development of a platform technology for high-throughput protein expression. The current standard for expressing panels of proteins involves extensive bioinformatics, cloning, in vivo expression, and assays. This method takes significant expertise in disparate fields, and weeks to months o ...

This SBIR Phase I project will develop a revolutionary new tool for creating engaging language-learning content. Educational publishers, teachers, and even students will be able to create artificially intelligent "virtual role-players" that converse in foreign languages, responding to either speech or text input. Large-scale on-line communities of educators will be able to create, customize, and s ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop odorant receptor function bioassays to provide services for companies that develop and formulate odors used in many kinds of commercial products. These services identify the biological sensors responsible for specific odor sensations and determine how these sensors are invol ...

The broader impact/commercial potential of this project is in developing a technologically advanced textile dye particle originating with plant material that will reduce water pollution, help alleviate stress on constrained water supplies, and improve factory worker health by creating a high performance, low water use natural dye for fabrics. Wet textile processing is the largest contributor to fr ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop reliable technology for the production of aptamer pairs. Aptamers are core reagents in emerging markets, regarded as alternatives to monoclonal antibodies in therapeutics, diagnostics, and imaging. They possess several appealing qualities: Ease of in vitro synthesis, flexibl ...