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"Extra Innings”: Using Serious Gaming and the Science of Baseball to Teach Science and MathematicsSBC: DFUSION INC. Topic: 999
DESCRIPTION provided by applicant Due to the rapid advances in science technology engineering and mathematics STEM the United States has been at the forefront of innovation and technology development in the science health and biomedical fields However these continuing advances are in jeopardy as there is a growing national shortage of trained STEM workers While the need for a STEM li ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in AthletesSBC: BIONIKS Topic: NIAMS
DESCRIPTION provided by applicant The mission of Bioniks is to develop and commercialize accurate low cost movement analysis systems for clinicians ergonomists athletic trainers and other professionals interested in quantifying human movement Our initial focus is on developing computer enhancements for inexpensive D cameras like the Microsoft Kinect These enhancements surpass the accura ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
Nanoliter electron paramagnetic resonance sensor based on diamond nanophotonics: a new tool for biomarker monitoringSBC: ODMR Technologies, Inc Topic: 400
DESCRIPTION provided by applicant ODMR Technologies Inc together with Victor Acostaandapos s group at University of New Mexico is developing a nanophotonic platform capable of uniquely detecting minute quantities of biomolecules The specific detection of biomolecules plays a central role in modern life science including cell systems biology high throughput drug scre ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
Development of a Genotype-linked Antibiotic Resistance Platform for Real Time Pathogen Risk Classification and EpidemiologySBC: MAVERIX BIOMICS, INC. Topic: NIAID
Project Summary Antibiotic resistance has become a pressing public health concern due to the rise of pathogenic bacterial strains with mutations that reduce or eliminate the effectiveness of drugs to treat infections Beta lactamases produced by some bacteria provide resistance by degrading beta lactams one of most widely used class of antibiotics Originally restricted to penicillins mutant bet ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: SEACOAST SCIENCE, INC. Topic: NIEHS
Project Summary This Small Business Technology Transfer Phase I project proposes the development and optimization of a commercially viable novel polymer based radiation dosimeter for wide spread deployment The radiation dosimeter proposed herein is a disruptive technology with a significant market Although many commercial radiation dosimeters measure individual radiation load dose quantificatio ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
Use of EF2K inhibitors to inhibit tumor growth and sensitize cancer cells to existing chemotherapy treatmentSBC: LONGEVICA PHARMACEUTICALS, INC. Topic: 102
DESCRIPTION provided by applicant Eukaryotic elongation factor protein kinase eEF K is a ubiquitously expressed protein that belongs to a family of alpha kinases characterized by an andquot atypicalandquot kinase domain Our recent findings demonstrate that inhibition or genetic inactivation of eEF K protects normal tissues from cytotoxic effects of ionizing radiation and chemotherapeutic ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
Development of a non-fibrillic amyloid-beta oligomer selective positron emission tomography imaging diagnostic for Alzheimer.SBC: Acumen Pharmaceuticals, Inc Topic: NIA
In the United States in an estimated million people suffered from Alzheimer s disease AD with as many as being undiagnosed Alzheimer s Association Three stages of AD are proposed National Institute on Aging and the Alzheimer s Association preclinical AD mild cognitive impairment MCI due to AD and dementia due to AD The preclinical stage is proposed to begin ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: BioIncept, LLC Topic: NICHD
ABSTRACT Perinatal hypoxic ischemic encephalopathy HIE affects to infants per every born Mortality from HIE can be up to and approximately of survivors suffer significant long term disability including cerebral palsy epilepsy and developmental disorders Damage during the acute phase of HIE is caused by a deficit in oxygen and glucose in the brain However increasing evide ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: AFASCI INC Topic: NIDA
DESCRIPTION provided by applicant The abuse of illicit drugs such as cocaine marijuana and heroin remains a critical public health concern throughout the country and is associated with staggering economic and social consequences Cocaine remains the most frequently recorded illicit drug in emergency hospital visits and the leading cause of drug related deaths in the United States Since as hi ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: ADEPTHERA, LLC Topic: NICHD
DESCRIPTION provided by applicant Preeclampsia is a pregnancy specific hypertensive disorder that can lead to multi organ failure seizure and maternal death Preeclampsia is also responsible for as many as of premature births in the United States Although better neonatal care has improved the likelihood of preterm babies surviving many face increased mortality and serious long term mor ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health