Award Data

We propose a next-generation reader system for Rapid Diagnostic Tests using lateral flow immunoassay cartridges. The system includes a rugged and lightweight reader that is built on a cellphone platform, a centralized data server, and bio-surveillance application software. The server communicates with readers securely over Internet, cellular and other networks. Reader design aims to provide the ...

HJ Science & Technology, Inc. proposes to demonstrate the feasibility of an integrated“lab-on-a-chip” technology capable of rapid and real time detection and identification of a variety of toxins in drinking water, particularly microcystins and other toxins produced by cyanobacteria. During blooms, the toxins in freshwater become concentrated enough to be a serious concern for ahuman health, ...

Environmental pollutants that impact critical biological pathways involved in human development and physiology can have unpredictable effect on health. Among these critical pathways, various receptor tyrosine kinases, sonic hedgehog, transforming growth factor beta, Notch and WNT are known or suspected mediators of the effect of numerous environmental toxicants produced during manufacturing, pres ...

The environmental impact of wood coatings has become a pressing issue as the manufacturing of wooden products such as flooring, cabinetry, furniture and doors is moving back to the United States amidst rising labor costs overseas. For the last thirty years the bulk of these products have been painted in countries with lax environmental regulations, allowing the use of inexpensive but environmenta ...

The proposed EPA SBIR Phase I program will create a novel ultra low power and low cost microfabricated CO2 sensor. The initial developments of sensor technology will serve the very large Demand Controlled Ventilation market that has been identified by KWJ and its collaborators. Phase I is dedicated to design, fabrication and testing of the innovative system consisting of a unique MEMS sensor, di ...

Breast cancer is not a disease of individual cells, but principally a failure of cells and tissues to communicate properly. One communication mechanism that is frequently disrupted in breast cancer involves the hormone estrogen. Despite recognition that exposure to compounds with estrogenic activity can promote breast cancer formation and progression, no good mechanistic explanation presently ex ...

Wastewater treatments minimize transmission of pathogens, and are required by the EPA with established treatment and monitoring requirements. The efficiency of treatment processes is determined by measuring the inactivation of indicator organisms (e.g., fecal coliforms) with culture-based techniques. Recently, Clostridium perfringens spores have been identified as excellent indicator organisms t ...

Electronic waste (e-waste) is one of the most rapidly growing waste problems worldwide. Improper handling of e-waste results in vast amounts of toxic waste being sent to landfill and leaching into the water supply. Due to these concerns e-waste recycling is a rapidly growing industry. Unfortunately, most current e-waste recycling processes rely on either manual hand sorting or differential dens ...

The project team is developing a prototype of the World Explorador game to deliver a learning experience that promotes basic language and literacy skills of English Learners. The games will be available on handheld mobile devices and will provide short, interactive language-rich learning activities intended to provide practice in specific skills. Pilot research in Phase I will seek to demonstrate ...

This project will develop SciSkillQuest, a web-based multiplayer game intended to teach middle school students scientific inquiry skills and to foster academic growth mindsets in science. Students will pursue quests, employing inquiry skills to navigate and succeed in the game, including Questioning, Modeling, Investigating, Analyzing, Computing, Explaining, Arguing, and Informing. The game will ...