Award Data

Combat soldiers are exposed to vast numbers of dangerous chemicals with potentially adverse health outcomes. This SBIR proposal aims to develop a new class of saliva based diagnostic assays that will measure the bodys response to toxic chemical exposure with a panel of clinically validated biomarkers that are indicative of organ injury. The tests will leverage the proven functionality of lateral ...

DoD requires a single, multiplexed, saliva-based diagnostic bioassay to determine multiorgan injury-relevant systemic toxicity. This assay should quantitatively-detect clinically relevant biomarkers in saliva and validate organ injury arising from chemical/xenobiotic exposure. Innosense LLC (ISL) is building on its proprietary carbon nanotube platform to construct Nano-Mos for detecting salivary b ...

The Defense Health Agency seeks to develop a universal, automated needle decompression device to more effectively manage tension pneumothorax on the battlefield. Critical Innovations and KARA & Associates, with consultants Captain David Tanen MD, FAAEM, F

Surgical trainingrequires an understanding of the human body’scomplex3-dimensional anatomical structures and thespatial relationships of nerves, blood vessels and othervital structures.Learningthesespatial skills requires a lengthy training period and much practicethat usually takes placein the operatingroom while under thesupervision of a senior surgeon atgreat financial cost and potential risk ...

Complete human anatomy avatars have a broad future role in advanced training environments, providing, for example, medically correct immersive experiences, performance-related physiological modeling studies, and in simulations for the purpose of designing protective armor. USARIEM have created individualized avatars as 3-D tetrahedral Finite Element (FE) meshes with full labeled anatomy, fitted to ...

To address the DHP and USAMRMC need for a system to augment a dynamic 3D scene registration using augmented reality (AR) to provide anatomically accurate registration and overlays to aid in medical training, Physical Optics Corporation (POC) proposes to develop a new Educational Medical Simulation and Training Augmented-Reality (EMSTAR) tool. The tool is based on the unique combination of low-cost ...

In this project, we propose to identify and examine solution growth approaches for engineering perovskite single crystal for gamma spectrometry in a hand-held sensor format. We will demonstrate that the solution growth approach is able to produce perovskite single crystal in sufficient volume and quality to yield a detector crystal whose utilization presents no inherent environmental, health, or s ...

Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

In a multiple patient situation, the medics need all the help they can get. Monitoring several patients is a difficult task, and associating the vital signs data with the right patient is crucial. Providing medics with a tool to assist in this task can gr