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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Single-cell Phosphoprotein Assay to Evaluate Brain Tumor Therapeutic Resistance

    SBC: IsoPlexis            Topic: 102

    Although signal transduction inhibitors occasionally offer clinical benefit for cancer patientssignal flux emanating from oncogenes is often distributed through multiple pathwayspotentially underlying the resistance which causes failure of most such inhibitorsMeasuring signal flux through multiple pathwaysin response to signal transduction inhibitorsmay help uncover network interactions that contr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Novel assay to monitor Tacrolimus levels at the point of care

    SBC: AFFINERGY, LLC            Topic: NIAID

    SUMMARY ABSTRACT Inoverorgan transplants were performed in the United Statesan increase ofover the pastyearsOrgan transplantation requires lifelong immunosuppression to prevent rejection of the transplantTacrolimusa macrolide antibioticis one of the most effective immunosuppressantswith andgtof solid organ transplant recipients receiving it as part of their maintenance immunosuppressionTacrolimus ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Near Patient Acute Kidney Injury Biomarker Analysis in Critically Ill Neonates

    SBC: Baebies, Inc.            Topic: NICHD

    Acute kidney injuryAKIcontributes to mortality and morbidity in critically ill neonatesThe identification and treatment of AKI are currently based on serum creatininesCrlevelshowevermounting evidence suggests that sCr alone is insufficient to predict or prevent renal injurysCr is in fact a measure of renal functionnot injurysCr levels usually rise many hours after a renal injuryrequire a substanti ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. New Class of Bright, Sharp, Tunable Near-Infrared Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: NIAID

    Abstract Polychromatic flow cytometryFCis one of the most powerful analytical techniques routinely used by both basic research and clinical diagnostics laboratories for the immunological categorization of cellsDyes used for FC typically exhibit broad fluorescent emission bands with full width at half maximumfwhmvalues ofnmThis limits the maximum number of dyesand thus the number of cell biomarkers ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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