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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NutraStem as a neuroprotectant: Implications for neurogenesis in HAART treated patients

    SBC: NATURA THERAPEUTICS, INC.            Topic: 213

    DESCRIPTION provided by applicant We designed an experiment to understand the interactions between loss of development of new neurons neurogenesis in the brain HIV Tat protein and the known cognitive side effects imparted by chronic highly active antiretroviral therapy HAART We preliminarily found the common HAART combination for HIV patients lamivudine zidovudine efavirenz TC AZT E ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Targeted Intraceptor Nanoparticle for Macular Degeneration

    SBC: Iveena Delivery Systems, Inc.            Topic: N

    DESCRIPTION provided by applicant Age related macular degeneration AMD is a leading cause of blindness in United States and many other industrialized nations There are two types of AMD the andquot dryandquot and andquot wetandquot forms Dry AMD is a chronic disease that usually causes variable degree of visual impairment In contrast in wet AMD which affects of AMD patients t ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A multi-analyte device for air quality monitoring

    SBC: TF HEALTH CORPORATION            Topic: NIEHS

    DESCRIPTION provided by applicant Air quality affects the health and well being of each of us especially those with chronic respiratory diseases Acute exposure to fatal levels of hazard materials causes millions of accidents every year and unnoticed long term exposure to lower levels of chemicals affect far more people Various technologies have been developed to monitor air quality but no ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Prevention of Proliferative Vitreoretinopathy by HC-HA/PTX3

    SBC: BIOTISSUE HOLDINGS INC.            Topic: W

    DESCRIPTION provided by applicant Proliferative vitreoretinopathy PVR is characterized by membranes that develop on the surface of the retina after rhegmatogenous retinal detachments RRDs Because PVR membranes exert tractional forces on the retina they are the leading cause of failure after RRD surgery Despite additional surgical interventions the visual outcome still remains poor Prev ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Isolation and Characterization of Low Molecular Weight Compounds Derived from Plant Extracts that Activate the IRS-2 Dependent Insulin Signaling Cascade.

    SBC: HOUSEY PHARMACEUTICAL RESEARCH LAB            Topic: 200

    DESCRIPTION provided by applicant This is a Phase I SBIR Application entitled andquot Isolation and Characterization of Low Molecular Weight Compounds Derived from Plant Extracts that Activate the IRS Dependent Insulin Signaling Cascade andquot Diabetes is a growing and significant global health concern Insulin Receptor Substrate IRS is a critical component in the insulin mediated s ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Easy, Affordable and Accurate Point of Care Screening to Reduce Colorectal Cancer Disparities

    SBC: Beacon Biomedical, LLC            Topic: NIBIB

    DESCRIPTION provided by applicant Colorectal cancer CRC is the second most common cause of cancer death in the US causing more than deaths each year Unfortunately African Americans AAs experience disproportionate incidence and mortality rates of CRC across all races in the US due to a complex interplay of economic social and cultural factors AAandapos s higher incidence lower r ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Treating Acute Lung Injury via Cytokine Signaling Blockade

    SBC: NAVIGEN, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Acute lung injury ALI and acute respiratory distress syndrome ARDS result from a common pathogenic process pulmonary injury or infection triggers an overwhelming inflammatory response andquot cytokine stormandquot that results in increased endothelial and epithelial permeability and efflux of inflammatory cells protein and water from the vascular syst ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. L-MOD Therapy: Leukocyte Immunomodulation during Cardiopulmonary Bypass

    SBC: Innovative Biotherapies, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant The Problem Cardiovascular disease is the leading cause of death in the Western world In the US nearly coronary artery bypass surgeries are performed annually with an estimated of these using the technique of cardiopulmonary bypass CPB CPB patients experience complications many of which are considered to be due to the activation of leukocytes ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Hand-held advanced functional imager for assessing local tissue oxygenation

    SBC: WASATCH PHOTONICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant We propose development of an advanced functional imager to assess red blood cell RBC transfusion The prototype will be tested in a functional phantom during this SBIR Phase I project The key features of the imager are the ability to quantify local tissue oxygenation with a handheld probe for easy tissue access Our preliminarily market research indicates a ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. HLS13-04 High-Content High-Throughput Screen for Diamond Blackfan Anemia Treatments

    SBC: Recursion Pharmaceuticals, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant There are thousands of rare genetic diseases that have no approved treatment Recursion Pharmaceuticals has developed a drug discovery platform that seeks to re purpose known drugs for the treatment of such diseases The platform consists of high content immunofluorescent image analysis using machine learning algorithms to identify relevant and on target chang ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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