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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TRAIL Upregulation by TIC10 Analogs

    SBC: PROVID PHARMACEUTICALS INC.            Topic: NCI

    Project Summary/Abstract TIC10 (ONC201) is a first-in-class antitumor agent and small molecule inducer of the TRAIL gene which was identified in a high-throughput small molecule library screen in the lab of our collaborator, Dr. Wafik El-Deiry at Penn State University and has been shown to have preclinical efficacy in several difficult-to-treat disease settings that include unmet clinical needs su ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Novel Fast GPU Monte Carlo and Active Photonics Simulation Softwar

    SBC: SIMPHOTEK, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Photodynamic therapy (PDT) is used for treating a variety of medical conditions including cancer. Even after many years of PDT research and the large-scale use of PDT treatments by physicians, there are many aspects ofPDT, such as quantitative predictions for diffusive light propagation and the kinetics of the light-material interactions, that are not well unde ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid Point-of-Care Salivary Diagnostic for Periodontal Health

    SBC: INNOVATIVE DIAGNOSTICS, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): The dental profession has searched for many years for additional real time chair-side measures to provide objective measures to aid in the monitoring of periodontal health and early diagnosis of disease. Research efforts have produced solid evidence that constituents present in saliva can provide important complimentary diagnostic information, and have the po ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. SGX942 to Decrease Oral Mucositis After Chemoradiation for Head and Neck Cancer

    SBC: Soligenix, Inc            Topic: NIDCR

    DESCRIPTION (provided by applicant): Oral mucositis has a significant impact on patient quality of life and outcomes during cancer therapy as well as having a significant pharmacoeconomic cost. There are no currently approved drugs to treat oral mucositisin patients with non-hematological malignancies, including head and neck cancer (HNC). Soligenix is developing a new compound, SGX942, a modulat ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Peer-to-Peer Mentoring Platform for Diabetes Management, Training and Support

    SBC: InquisitHealth, Inc.            Topic: NIDDK

    ABSTRACT The Specific Aim of this proposal is to test the feasibility of developing a web-based peer mentor training and mentor-mentee matching system to help patients better manage their diabetes through mentoring. Effective self-management of diabetesis the key to improving diabetes outcomes and reducing costs. Self-management includes medication adherence, self-monitoring, healthy eating, and ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Infrared Eyes

    SBC: EDEN MEDICAL, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Eden Medical, Inc. is pleased to submit this Phase 1 SBIR proposal to develop the Infrared Eyes (iREyes) imager system, an affordable and powerful mobile health (mhealth) tool for healthcare. The hand-held iREyes system will acquire both thermal and visible spectrum imagery to quantify healing via foot thermal indexing methodology. The iREyes will offer a use ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Wearable Monitor for Recording the Activity of Brown Adipose Tissue

    SBC: MMTC, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Brown Adipose Tissues (BAT) are tissues that when activated become metabolically active and take calories from normal white fat and burn them. Safe methods for creating and activating (BAT) would therefore be of great value in fighting obesity, a leading preventable cause of death with increasing prevalence in adults and children and one of the most serious pub ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Magnetic Tracking and Orientation of Imaging Endoscopic Capsules

    SBC: Koronis Biomedical Technologies Corp.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Prior to the advent of capsule endoscopes (CE), imaging and examination of the small bowel was difficult. Today, a patient swallows the capsule with an imaging camera, which is then carried passively through the gastrointestinal (GI) tract by peristalsis. The onboard camera captures images of the lumen wall several times per second over a 7-11 hour period, rela ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a porcine model of polycystic kidney disease by multiplex gene-editing.

    SBC: Recombinetics, Inc.            Topic: NIDDK

    ? DESCRIPTION (provided by applicant): Polycystic kidney diseases (PKD) are a group of inherited disorders characterized by progressive cyst development in the kidney resulting in bilateral renal enlargement and often end stage renal disease (ESRD). The most common form of PKD, autosomal dominant PKD occurs at a frequency of 1:400 to 1:1000. Currently, there is no treatment that can slow or re ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Novel reporter cell lines for neurotoxicant assays

    SBC: TRANSPOSAGEN BIOPHARMACEUTICALS, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): While it has been demonstrated that gene mutations are associated with an increasing number of neurodegenerative syndromes, environmental neurotoxicants remain a key factor in the etiology of many such diseases. For example, exposure to pesticides such as maneb and paraquat increase the risk of developing Parkinson's disease. Unfortunately, there is no opt ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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