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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Formulation & Evaluation of Bioadhesive Gels for Oral Cancer Chemoprevention

    SBC: NANOMED PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Despite concerted efforts to improve therapy, five year survival rates for patients with advanced stage oral squamous cell carcinoma (SCC) remain discouragingly low. Clearly, early detection combined with strategies for local intervention, such as chemoprevention prior to SCC development, could dramatically improve clinical outcomes. The results of previously c ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Multiplexed Ultrasensitive Mix-and-Read Tumor Marker Quantification Assays

    SBC: NESHER TECHNOLOGIES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Nesher Technologies, Inc. (NTI) licensed from UCLA the IP for a revolutionary suite of ultrasensitive biodetection technologies involving alternating laser excitation (ALEX) fluorescence spectroscopy. These technologies were developed at the UCLA Single Molecule Biophysics Laboratory (headed by Prof. Shimon Weiss). NTI proposes to apply one of these technologie ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Vaccine Strategies for Candidal Infections

    SBC: NOVADIGM THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Candida is a fungus that is among the most common causes of infections in hospitalized patients in the United States and worldwide. Candida spp. are one of the most common microbes that infect the blood and urine of hospitalized patients. The cost associated with Candida blood infections alone exceeds at least $1 billion per year in the US. Even with therapy, 4 ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Comparative systematic genetics for cardiovascular disease gene identification

    SBC: Fabric Genomics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal will lead to identification of gene variants that increase the risk of developing cardiovascular disease. The underlying hypothesis is that systematic genetics conducted in model organisms enables the identification of disease-specific gene modules. This hypothesis will be tested in Phase I through the following Aims: (1) Create a database of phen ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. High Adherence Ergonomic Oral Positive Airway Pressure Device

    SBC: OPAP, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of a miniature orally inserted blower with embedded sensing for the diagnosis and treatment of sleep disordered breathing is proposed. This Oral Positive Airway Pressure (OPAP) device represents a potentially radical change in the interface, machine, and patient adherence of sleep disordered breathing treatment. The ergonomic design of the device w ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Adaptive camera to display mappings using computer vision

    SBC: POLAR RAIN, INC.            Topic: N/A

    The video surveillance industry is experiencing dramatic change with the move from analog to digital video. Command centers need to have coordinated viewing of multiple camera feeds at one time, and the ability to switch automatically between feeds and display relevant patterns. Conventional security control rooms include a bank of monitors connected through a switch to an array of security camera ...

    STTR Phase I 2006 Department of Homeland Security
  7. Family Empowerment: Adapting Successful Disclosure Strategies for HIV+ Parents

    SBC: SCIENCE2MARKET, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): One million adults in the US and 42 million families globally must decide if, to whom, when, and how to disclose their HIV+ serostatus. Often, disclosure of serostatus has a long-term negative impact on children and extended family members of HIV+ parents; this team has developed a coping-skills intervention that can positively impact the adjustment over 6 year ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Micro-Targeting Capillary Ballistic Delivery System

    SBC: Seashell Technology LLC            Topic: N/A

    Methods for the delivery of therapeutics, tracking dyes, genes and other substances into complex neural tissue, organotypic cultures and cell types are limited in their effectiveness. The biolistic process, based upon acceleration of carrier particles to sufficient velocity, has recently been shown to be a relatively effectual delivery method for neuronal systems. However, cell damage and tissue d ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Recombinant system for ultra-large scale biomanufacturing of therapeutic proteins

    SBC: SOLAZYME, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Solazyme, Inc. in collaboration with the City University of New York (CUNY) proposes to develop a novel recombinant protein expression platform by transforming the photosynthetic microalgal species Dunaliella salina. The organism's autotrophic production of nutrients from sunlight and extreme halotolerance will allow new biomanufacturing processes to overcome t ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Device for Acamprosate Transcutaneous Delivery to Reduce Alcohol Consumption.

    SBC: Technova Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Alcohol dependence is a chronic disorder with genetic, psychosocial, and environmental underpinnings. Alcohol's societal impact is widespread; it is estimated that there are 17.6 million individuals who abuse or depend on alcohol in the United States. (Grant et al, 2004). Alcohol dependence is considered the third leading preventable cause of death in the Unite ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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