You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. CELL SORTING BY PHOTO-ACTIVATED DYE TAGGED ANTIBODIES

    SBC: CANDELA CORPORATION            Topic: N/A

    CANDELA LASER CORPORATION AND UCLA TISSUE TYPING LABORATORY PROPOSE TO DEVLOP A GROUP OF DYE TAGGED MONOCLONAL ANTIBODIES AND A LASER TO TARGET THESE DYES, FOR THE PEREFERENTIAL DESTRUCTION OF HUMAN T CELLS FROM A MIXTURE OFT AND B CELLS AND ALSO ACINAR CELLS IN THE PRESENT OF SLIT CELLS. THE ENVISIONED PROCEDURE IS TO ATTACH SPECIALLY MODIFIED DYES TO MONOCLONAL ANTIBODIES. THE MONOCLONALS WILL T ...

    SBIR Phase I 1988 Department of Health and Human Services
  2. PULSED DYE LASER AB-INTERNO SCLEROTOMY

    SBC: CANDELA CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  3. STANDARDIZED CONTRAST AGENT FOR NEUROSONOGRAPHIC IMAGING

    SBC: Cavitation-control            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  4. NOVEL HLA-LINKED DNA IN A YEAST ARTIFICIAL CHROMOSOME

    SBC: CBR LABORATORIES, INC.            Topic: N/A

    ALTHOUGH A LARGE NUMBER OF DNA CLONES EXIST WHICH COVER MANYOF THE GENES OF THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX (MHC), A NUMBER OF LARGE GAPS EXIST, INCLUDING THE 275-300 KB REGION OF DNA BETWEEN HUMAN LEUCOCYTE ANTIGEN (HLA)-DR AND THE COMPLEMENT GENES. THE MHC ENCODES GENES DETERMING SUSCEPTIBILITY TO DISEASE, INCLUDING JUVENILE-ONSET DIABETES, GLUTEN-SENSITIVE ENTEROPATHY, AND THE BLISTE ...

    SBIR Phase I 1988 Department of Health and Human Services
  5. ASSAYS FOR HEPATITIS B VIRUS WITH HUMAN LEUKEMIC CELL LINES

    SBC: CBR LABORATORIES, INC.            Topic: N/A

    INFECTION OF HUMANS WITH THE SMALL HEPATOTROPHIC DNA VIRUS, HEPATITIS B VIRUS (HBV), CAN LEAD TO ACUTE OR CHRONIC HEPATITIS, CIRRHOSIS AND PRIMARY HEPATOCELLULAR CARCINOMA. IN SPITE OF ADVANCES IN TESTING OF BLOOD AND THE RECENT INTRODUCTION OF A SAFE EFFECTIVE VACCINE, THERE IS STILL AN INCIDENCE OF ABOUT 6% INFECTION BY HBV IN INDIVIDUALS WHO RECEIVE A BLOOD TRANSFUSION OR BLOOD PRODUCTS. THUS T ...

    SBIR Phase I 1988 Department of Health and Human Services
  6. CRYOPRESERVATION OF PANCREATIC ISLET CELLS

    SBC: Cellular Transplantation            Topic: N/A

    DIABETES MELLITUS IS ONE OF THE MOST PREVALENT, MORBID AND MORTAL DISEASES KNOWN TO MANKIND. TRANSPLANTATION OF PANCREATIC ISLETS IN ANIMAL MODELS CAN COMPLETELY CURE DIABETES AND MORE IMPORTANTLY MAKE THE ANIMAL ABSOLUTELY INDEPENDENT OF INSULIN. THE SUCCESSFUL TRANSPLANTATION OF ISLETS CAN BE FACILITATED IN A CLINICAL SITUATION IF ADEQUATE MEANS OF PRESERVING ISLETS ARE AVAILABLE. THE OVERALL LO ...

    SBIR Phase I 1988 Department of Health and Human Services
  7. SYNTHESIS OF FLUORESCENT INDICATORS FOR CYTOSOLIC CA2+

    SBC: COVALENT ASSOC., INC.            Topic: N/A

    A SERIES OF IMPROVED FLUORESCENT DYES SPECIFIC FOR COMPLEXING CA2+ WILL BE SYNTHESIZED AND EVALUATED FOR THEIR ABSORPTION AND EMISSION CHARACTERISTICS AND THEIR ABILITY TOBIND CA2+. THESE CHELATORS INCORPORATE BENZOCOUMARIN LASER DYE FLUOROPHORES, WHICH HAVE DESIRABLE HIGH-QUANTUM YIELDS AND VISIBLE WAVELENGTH ABSORPTION AND EMISSION. THE FLUOROPHORE IS ATTACHED TO AN EGTA-LIKE (ETHYLENEGLYCOL BIS ...

    SBIR Phase II 1988 Department of Health and Human Services
  8. SOFTWARE FOR GROUP-SEQUENTIAL CANCER CLINICAL TRIALS

    SBC: CYTEL SOFTWARE CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  9. ARTICULATION TRAINING AID

    SBC: Design Automation Associates            Topic: N/A

    A CONCEPT HAS BEEN DEVISED FOR THE APPLICATION OF MODERN SPEECH-RECOGNITION TECHNIQUES TO ASSIST IN ARTICULATION TRAINING OF PERSONS WITH SPEECH DEFICITS OR RELATED LEARNINGDISABILITIES. PROPOSED IS A DEVELOPMENT EFFORT TO EMBODY THE CONCEPT IN SOFTWARE AND ADD-ON HARDWARE FOR A PERSONAL COMPUTER TERMINAL. IT IS EXPECTED THAT THIS TRAINING AID WOULD BE UTILIZED AT FIRST, AT SPEECH AND LANGUAGE CLI ...

    SBIR Phase I 1988 Department of Health and Human Services
  10. A STRABISMUS CORRECTING PROSTHESIS

    SBC: Dsp Engineering Inc            Topic: N/A

    TREATMENT OF STRABISMUS REMAINS A SIGNIFICANT CHALLENGE TO THE FIELD OF OPHTHALMOLOGY. A NEW APPROACH HAS BEEN TAKEN TO TREAT THIS CONDITION WHICH PROVIDES A LEVEL OF PRECISION AND FLEXIBILITY UNOBTAINABLE VIA SURGICAL AND/OR PHARMOCOLOGICAL MEANS. THE WELL-ESTABLISHED TECHNIQUE OF ELECTRICAL STIMULATION TO PRODUCE CONTROLLED MUSCLE CONTRACTION HAS BEEN EMPLOYED IN A NOVEL WAY. A PROSTHESIS SYSTEM ...

    SBIR Phase I 1988 Department of Health and Human Services
US Flag An Official Website of the United States Government