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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Low Cost Co-Doped Scintillator for Medical CT

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Venous catheters play critical roles in the administration of chemotherapy, antibiotics, blood, blood products and total parenteral nutrition essential for the successful treatment of many chronic afflictions. Recent ad vances in catheter technology have enabled the explosive growth in oncology (vascular access ports), nephrology (hemodialysis catheters) and in ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Production and use of Pb-203 for cancer therapy research

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Promising results are being obtained from studies of molecules labeled with Lead-212 (Pb-212) as potential targeted radiotherapeutic agent against metastatic melanoma. According to the American Cancer Society approximat ely 60,000 people in the US will be diagnosed with melanoma this year, and 8,000 will die from this disease. For Pb-212 melanoma therapy to pro ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. ADVANCED TECHNOLOGY FOR ASSAYING CANCER-DRUG RESISTANCE

    SBC: AMBERGEN, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Significant advances have been made toward the development of a new generation of molecularly targeted cancer drugs, many of which are only now emerging from the pipeline. This project aims to develop a new, highly sens itive technology for detecting drug-resistance mutations in proteins which preexist prior to treatment or are acquired due to the selective pre ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. HEMOGLOBIN DERIVATIVES AS BLOOD SUBSTITUTES

    SBC: ANATRACE, INC.            Topic: N/A

    THE USE OF BLOOD AND BLOOD PRODUCTS IS EXTREMELY IMPORTANT IN THE TREATMENT OF MANY PATIENTS IN SERIOUS OR CRISIS SITUATIONS. THE VALUE OF THESE MATERIALS, AND PARTICULARLY WHOLE BLOOD, HAS SERVED TO EMPHASIZE THE PROBLEMS IN PROVIDING THEM IN ALL APPROPRIATE CIRCUMSTANCES. THE USE OFBLOOD REQUIRES STORING OF AN ADEQUATE SUPPLY FOR ALL POTENTIAL EMERGENCIES AND CAREFUL CROSSMATCHING BEFORE USE. IN ...

    SBIR Phase I 1988 Department of Health and Human Services
  5. D9-THC for Marijuana Addiction

    SBC: APHIOS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): ?9-tetrahydrocannabinol (?9-THC) has been shown to alleviate marijuana withdrawal symptoms and thus has potential for treating cannabinoid dependence. However, the bioavailability of ?9-THC administered orally is poor a nd variable. In addition, it also requires drug administration several times a day. Formulations to improve bioavailability and/or to reduce do ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. 402- RFP: N43-CM-87007-68 TOPIC 251: DEVELOPMENT OF ANTICANCER AGENTS REQUEST

    SBC: APHIOS CORPORATION            Topic: N/A

    The aim of this project is the development of Tyrosyl DNA phosphodiesterase (Tdp1) inhibitors in order to enhance the activity of DNA topoisomerase I inhibitors.

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. ATTENUATION OF THE NYCBH VACCINE STRAIN OF VACCINIA

    SBC: APPLIED BIOTECH CONCEPTS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  8. THERAPY AGAINST RECALCITRANT C. albicans INFECTION

    SBC: ARIETIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this project is to develop an effective therapy against relapsing vaginosis caused by Candida albicans. The disease occurs in 8-9% of all women, and is recalcitrant to currently available therapies . Upon adherence to a surface, C. albicans forms persister cells which are tolerant to currently available antimicrobials. Known compounds alon ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Therapeutic Potential of Ex vivo expanded Human Cord Blood derived CD133+ cells i

    SBC: Arteriocyte, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Critical Limb Ischemia (CLI) is a common problem that often results in major limb amputation. Circulating endothelial progenitor cells likely play a role in the pathogenesis of CLI; the number and function of these cell s that are mobilized from the bone marrow are reduced in the elderly and diabetics, groups at high risk for CLI. Allogenic Umbilical Cord Blood ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Antibody therapeutics- feasibility study on hormone-refrectory prostate cancer m

    SBC: ATTOGEN, INC            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to evaluate the therapeutic feasibility of a humanized antibody drug DAPI- 01 (anti-FGFR2-IIIc) in prostate cancer model systems. The molecular target of the antibody is fibroblast growth factor receptor-2 (F GFR2) isoform IIIc, which is involved in androgen-independent tumor growth and metastasis. Our specialized antibody drug is designed with the i ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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