Award Data

Radionuclide guided intraoperative probes increase the specificity of tissue biopsiesenable minimalaccess incisionsreduce inpatient hospital utilizationand contribute to improved patient recoveryAt presentmost such probes on the market are non imagingand provide no ancillary information of surveyed areassuch as clear delineations of malignant tissuesOur goal is to develop a revolutionary new imagi ...

Project Summary The proposed program aims to quantify farmworker exposure to pesticides using Surface Enhanced Raman SpectroscopySERSand an inexpensive sensor which can also be used for urinalysisAn earlier programsupported by NIEHSprovided reliable results for organophosphateOPand organochlorineOCpesticidesFifty OP and OC pesticides and metabolites were evaluated in the laboratory in the low ppb ...

PUBLIC DESCRIPTION Akston is developing a subcutaneously administered therapeutic for preventing or delaying the onset of diabetes in pre diabetic patients who are at high riskthose who display autoantibodies for insulinGADIAand ZnTfor developing TypediabetesT DThe therapeutic is designed to delete a subset of B cells that likely play a role in disease development using a patient s own antibody di ...

Results of Phase II research indicate that formal validation of the EpiAirwayin vitro human bronchial tissue model for predicting toxicity of inhaled chemicals is an attainable goalThe proposed Phase IIB cooperative agreement project is intended to realize this goal by conducting formal ring trial validation studies that will be submitted to regulatory agencies and the Organization for Economic Co ...

PROJECT SUMMARY This project proposes to continue the development of AutoRegisterTMan integrated software based system for enhancing the accuracy of tumor change detectionThe intent of the system is to automate the alignment of a patient s brain scan with that of a prior scan such that subsequent offline tumor measurements do not have error introduced solely by differing slice orientationsWhile si ...

ABSTRACTThe overall goal of this Phase II project is to validate novel leishmanial protein biomarkers for development of a non invasive urine based assay to diagnose active visceral leishmaniasisVLand to monitor the therapeutic efficacy of this serious diseaseVL is endemic incountriesaffectspeople a year and kills more thanof them children under ageVLalso known as kala azaris caused by parasites o ...

TheWHO guidelines recommend anti retroviral therapyARTfor all HIV infected peopleand massive efforts to expand ART access will result in andgtM adults and andgtM children on ART byat a cost of almost US$BConsequentlythe number of patients prescribed alternativeprotease inhibitorPIbased ART following failure of first line regimens will also increaseStudies of patients on PI based ART in resource li ...

DESCRIPTIONprovided by applicantWrist worn Sensors for Tele Rehabilitation of the Hemiparetic Upper ExtremityStroke and other causes of central nervous system damage can result in debilitating loss of motor control that is often more pronounced in one limb than the otherUsing or attempting to use the affected limb during activities of daily livingdespite considerable difficultystimulates neuroplas ...

Project Summary First episode psychosis is a serious mental health condition that affects youth and young adultsoften between the ages ofandThe illness is marked by hallucinationsdelusionswithdrawalpoor organization skillsand diminished cognitive and social functioningRecent research has demonstrated that programs designed to treat people experiencing early psychosis can reduce hospitalizationdecr ...

Warehouse injuries and accidents are occurring much too frequently and resulting in devastating consequences and implications for the involved facility. Although the recent emergence of low-cost and unobtrusive sensor technologies have flooded nearly every market to improve health and safety, the warehousing and manufacturing markets have remained largely unpenetrated. Aptima plans to fill this ga ...