Award Data

R-LAM (Rad-hard Location and Attitude Module), promises a new generation of both integrated navigation modules and stand-alone navigation subsystems including nav-grade IMU's, atomic-precision clocks and GPS units compliant with the Space Plug and Play Architecture (SPA) initiative. R-LAM leverages two active DARPA MTO programs. In the Navigation-Grade Integrated Micro-Gyroscope (NG-IMG) project ...

Gun barrel bores have been traditionally plated with chromium to reduce erosion and increase barrel life. However, the chrome electro deposition process generates hazardous waste and the DoD has been moving to eliminate its use. Liners made from Tantalum-Tungsten (Ta-W) alloys have been shown to be an acceptable substitute. These alloys have a high melting temperature, are more erosion resistant t ...

RAVEN technology weapons vent a significant portion of the propellant gases rearward. Therefore the ammunition must allow the gun gases to leave the chamber at the proper time. This is in complete contrast to conventional weapons where the ammunition provides the breech seal during the entire ballistic cycle. As such, the technologies are incompatible and separate supply logistics must be main ...

DESCRIPTION (provided by applicant): Critical Limb Ischemia (CLI) is a common problem that often results in major limb amputation. Circulating endothelial progenitor cells likely play a role in the pathogenesis of CLI; the number and function of these cells that are mobilized from the bone marrow are reduced in the elderly and diabetics, groups at high risk for CLI. Allogenic Umbilical Cord Blood ...

DESCRIPTION (provided by applicant): Arteriocyte's long-term objective is to develop a platform for ex vivo expansion of leukemic stem cell (LSC) based on cytokine-enriched medium and the company's proprietary nanofiber culture scaffold (NANEX). Cancer stem cell research is of significant importance because, this approach has the potential to create an effective therapy that overcomes challenges o ...

DESCRIPTION (provided by applicant): A Phase 1 SBIR program of pre-clinical development is proposed focusing on a novel rapid-acting insulin analog for the treatment of diabetes mellitus. Designated Insulin-Cl, our product is a derivative of insulin lispro (the active component of HumalogTM) containing a single chloro-substitution within the aromatic ring of a conserved phenylalanine in the B-chai ...

DESCRIPTION (provided by applicant): A Phase 1 SBIR program of pre-clinical development is proposed focusing on a novel long-acting insulin analog for the basal treatment of diabetes mellitus. Designated Insulin-ZN, our product is a derivative of human insulin containing novel zinc-binding sites at the periphery of the insulin hexamer. The non-classical zinc-binding sites are mediated by paired (i ...

DESCRIPTION (provided by applicant): Peripheral Vascular Disease (PVD) results from chronic loss of the oxygen supply to the lower limbs due to arterial blockage. Loss of oxygen to these tissues can result in pain, ulcers, infection and limb amputation in patients. PVD affects up to 12% of the population globally with increased risk in patients with diabetes, hypertension, advanced age and obesity ...

We propose to implement a platform based on the .NET Micro Framework (MF) for mote-scale Wireless Sensor Networks (WSNs) and Active Tag Networks (ATNs). The resulting middleware would significantly simplify the development of applications on these systems, both by providing a hardware-independent, high-level, development environment and by providing standard implementations for essential services ...

Under the Phase I program, ASI will examine the available technologies for improving manipulation, create preliminary designs of how to integrate these technologies on current platforms (the Talon and Packbot), and simulate the effects of improved dynamic modeling and sensor feedback on manipulator performance. The deliverables for Phase I will thus be: • Preliminary design of retrofit packa ...