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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 31 - 40 of 3886 results
  1. Treatment of status epilepticus and refractory status epilepticus with intravenous topiramate.

    SBC: PREVEP, LLC            Topic: NINDS

    Abstract Status epilepticus (SE) is a common neurologic emergency that fails to respond to first- and second-line anti-seizure medications (ASMs) in about one third of instances, thus progressing to refractory SE (RSE). Patients with RSE are at grave risk for neurological morbidity and mortality. The recently completed NIH-funded Established SE Treatment Trial (ESETT) highlights the need for impro ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Prophylactic Immunotherapy for Marburg Virus Disease Outbreak Control

    SBC: ABVACC, INC.            Topic: NIAID

    The ebolaviruses (EBOV, SUDV, BDBV) and marburgviruses (MARV and RAVV), cause periodic outbreaks of severe viral hemorrhagic fever with very high mortality rates. The 2013-2016 Ebola virus disease (EVD) outbreak in West Africa highlighted the serious nature of a filovirus epidemic and its regional and global implications. This outbreak took an enormous toll on people at the front line of the epide ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Simple and Accessible Microfluidic Platform for Single Molecule Sequence Profiling of Tumor-derived DNA within Liquid Biopsies

    SBC: HYPERMELT, LLC            Topic: 394

    Project Summary/ Abstract Over 600,000 people in the US will die from cancer this year. It is estimated that 25% of these deaths could have been prevented by detection in earlier stages. Implementation of minimally-invasive routine screening, such as pap smears for cervical cancer, has proven to be an effective approach for reducing cancer mortality. However, several challenges prevent successful ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Staph Aureus Vaccine

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: NIAID

    Abstract Methicillin-resistant Staphylococcus aureus is often considered the prototype hospital-acquired infection. In spite of the billions of dollars spent on preventive measures, estimates of the incidence are in the hundreds of thousands, with tens of thousands of people per year succumbing to disease in the USA alone. Prophylactic vaccines against S. aureus would have an enormous impact in th ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. ADHERE (Applying Directly observed therapy to HydroxyurEa to Realize Effectiveness)

    SBC: EMOCHA MOBILE HEALTH INC.            Topic: NHLBI

    Summary/Abstract: Sickle cell disease (SCD) is a severe inherited blood disorder that leads to frequent acute and costly long-term complications. Hydroxyurea is the primary SCD modifying medication in childhood because studies show that it can reduce acute complications and mitigate costly long-term comorbidities. Hydroxyurea non-adherence is common, however, and a key reason for the limited impac ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Group B Streptococcus bioconjugate vaccine

    SBC: VaxNewMO            Topic: NIAID

    PROJECT SUMMARY Streptococcus agalactiae, commonly referred to as Group B Streptococcus (GBS), is a leading cause of neonatal meningitis and sepsis worldwide. GBS neonatal disease manifests as early onset invasive disease, defined as disease between birth and 6 days of life, or late onset invasive disease, defined as disease occurring between 7 and 89 days. In some instances, early onset disease i ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Thiazolino-Pyridone Compounds as Novel Drugs for Tuberculosis

    SBC: FIMBRION THERAPEUTICS INC            Topic: R

    Project Summary/Abstract Tuberculosis (TB), caused by infection with the bacterium Mycobacterium tuberculosis (Mtb), is a leading cause of mortality due to infection, globally. In 2020, 10 million people were newly diagnosed with TB and 1.5 million people died from the disease. As efforts to treat TB expand, the prevalence of infections caused by drug-resistant Mtb strains (DR-TB) that are resista ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Previvors Recharge: A Resilience Program for Cancer Previvors

    SBC: Pro-Change Behavior Systems, Inc.            Topic: 102

    It is estimated that approximately 5-10% of all diagnosed cancers are caused by Hereditary Cancer Syndromes (HCS) that are associated with germline mutations (inherited genetic mutations passed directly from a parent to a child that create a genetic predisposition to certain types of cancer). Recent epidemiologic models indicate that 1 in 279 people may be carriers of one of the most common HCS, a ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Beat Extreme: An Interactive, Tailored Text Messaging Program Combining Extreme Weather Alerts with Hyper-localized Resources and Actionable Insights for Addressing Climate Change

    SBC: Pro-Change Behavior Systems, Inc.            Topic: R

    Summary Climate change is an urgent public health threat, and climate-related health risks disproportionately impact vulnerable populations. Public health agencies have underscored the need to develop scalable and innovative health-equity centered, multi-level interventions that offer tools and resources to 1) raise awareness of the inextricable link between climate change and health and 2) suppor ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Extraction of Vital Signs using a Telehealth Application for Asthma- EViTA-AThe purpose of this grant is to evaluate mobile devices to extract vitals signs to monitor patients with Asthma

    SBC: M5 ENTERPRISE LLC            Topic: NHLBI

    Asthma is a chronic disease that affects quality of life, productivity, and healthcare use, and can ultimately lead to death. The costs of asthma are largely due to uncontrolled disease and accordingly rise as its prevalence and severity increase. Unfortunately, the incidence and impact of asthma attacks have not improved despite widespread adoption of effective universal treatment guidelines by h ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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