Award Data

In this proposal, we propose to demonstrate and build a near 2 micron widely tunable, narrow linewidth, single frequency fiber laser by developing an innovative Ho-doped single mode fiber. Such near 2 micron fiber laser is needed for coherent lidar and interferometric fiber sensing. In Phase I, we will design and fabricate this new fiber, demonstrate fixed wavelength narrow linewidth single freque ...

Both ground and space telescopes employ aspheric mirrors. A particular example is the X-ray telescope where primary and secondary mirrors have nearly cylindrical surfaces. Computer Generated Holograms (CGH), in combination with commercial interferometers, provide high resolution and high accuracy measurements of aspheric optical surfaces. The current state of the art CGHs are made on 6" square sub ...

DESCRIPTION (provided by applicant): The counterfeit drug business originated with lifestyle drugs, such as the erectile dysfunction drug. Now, however, counterfeits in almost any therapeutic category may be purchased by Americans through internet pharmacies. In fact, the Pharmaceutical Safety Institute found in 2010 that counterfeits in the metabolic disease category grew fastest (2), with the tr ...

DESCRIPTION (provided by applicant): Excessive alcohol use is associated with a range of serious and costly health, social, and economic consequences at the individual and societal level. This program of research serves as a venue by which to produce and test an innovative, science-based, and cost-effective means to intervene in a private, convenient, and individualized way with employed adults wh ...

DESCRIPTION (provided by applicant): This application proposes to build on the successful Phase I Picture Me Alcohol Free (PMAF) feasibility pilot study. PMAF is a community-based program designed to train groups of youth to a) represent contributing factors and consequences (e.g., social availability, alcohol-involved crashes) of underage drinking in their communities through a specific photograp ...

DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

DESCRIPTION (provided by applicant): We propose to develop an operating-room-ready system for needle guidance in soft tissue, which fuses intra- operative ultrasound and pre-operative X-ray computed tomography (CT) data by combining two novel technologies:1) a radically different way of visualizing and interacting with the fused ultrasound and CT images, which we call Spotlight ; and 2) an innova ...

DESCRIPTION (provided by applicant): Cachexia-anorexia syndrome is a life-threatening aspect to many diseases, in particular many forms of cancer or therapies for cancer. The obvious symptoms of this disease include lack of appetite, and a loss of lean body mass disproportionate to the reduction in caloric intake. However, the less obvious effects include multi-organ failure, due to high metabolic ...

DESCRIPTION (provided by applicant): Juvenile crime imposes enormous costs on victims, on society, and on juvenile offenders themselves. However, research assessing the efficacy of interventions for young offenders show, on average, only small effects on recidivism, substance abuse, and other behavioral outcomes. A major problem with existing interventions is that they tend to neglect individual d ...