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SBC: VOX BIOMEDICAL LLC Topic: NIDA
Project Summary This proposal seeks to expand upon breath analysis technology that is being actively studied as the focus of NIH grant #6R42DA049655-02 and leverage this technology for rapid COVID-19 diagnostics. There is a dire need for sensitive and specific diagnostic tests for COVID-19 that can be performed quickly. The differential mobility spectrometry (DMS) breath analysis technology curren ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: VELUM INC Topic: NIGMS
PROJECT SUMMARY Peptide therapeutics combine high potency and selectivity with fewer side effects than traditional small moleculesThis has fueled interest in peptides filling the gap betweenbiologicsand small molecules as compounds that have the key desired properties from both the other classesWorldwide peptide drug sales surpassed $billion inof which nearly $billion was in the USAwith projected ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Testing the feasibility of Rendever with older adults with cognitive impairments and their adult children.SBC: RENDEVER, INC. Topic: NIA
Alzheimer s disease affects approximatelymillion AmericansNIAand bythis number is expected to more than double tomillionUntil cures for the dementias are discoverednew technologies are imperative that can help reduce the emotional burden of AD ADRD for older adults and their care giversGoal C of NIA s strategic planIn this STTRSmall Business Technology TransferPhase I studywe test the feasibility ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: TRICORDER ARRAY TECHNOLOGIES LLC Topic: 100
PROJECT SUMMARY The for profit small business concernTricorder Array Technologies LLCwill developin partnership with the University of Alabama at BirminghamSIDECAReSensing and Integrating Data for Environmental Conditions in Animal ResearchThis device will automate collection of relevant data that will enhance consistency in animal models used to study human health treatment researchOur innovative ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: PNEUMAX, LLC Topic: 113
PROJECT SUMMARYThree of top five causes of death in humans globally are lung relatedchronic obstructive pulmonary diseaseCOPDlower respiratory infections and lung cancers collectively account for over eight million deaths annuallyCurrentlyin preclinical settingstatic cell cultures and animal models are the most widely used systems for mechanistic and translational studiesHowevercritical limitation ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Equiti Foods, LLC Topic: 102
Abstract Emerging data indicate that those with pre-existing health conditions, such as obesity, diabetes, and heart disease, are at significantly increased risk of contracting COVID-19, as are low income and persons of color. Research also suggests that food insecurity (lack of access to affordable, nutritionally valuable food) and poor dietary intake are likely contributors to health disparities ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
A New Non-Invasive Approach for Accessing Pulmonary Arterial Stiffness in Patients with Pulmonary HypertensionSBC: ARCUS-MED LLC Topic: NHLBI
Pulmonary hypertensionPHis a disease affecting approximatelyof the general population that is characterized by abnormally elevated mean pulmonary artery pressuremPAPand pulmonary vascular resistancePVRIf left untreatedPH can ultimately lead to right heart failure and deathCurrent diagnostic approaches utilize invasive right heart catheterizationRHCto measure mPAP and PVREarly detection of PH leads ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: CFD RESEARCH CORPORATION Topic: DHA19A001
Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause oSTTR Phase I 2019 Department of DefenseDefense Health Agency
SBC: Periomics Care LLC Topic: NIDCR
Abstract Periodontitis is a common chronic inflammatory disease characterized by destruction of the supporting structures of the teeththe periodontal ligament and alveolar boneThe total prevalence of periodontitis in adults agedyears and older wasrepresenting aboutmillion adults agedyears and olderandin adults agedyears and older in the U SEpidemiological data confirm that diabetes is a major risk ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Extending WAAVES+: An animal and environment-agnostic, automated USV scoring platform for high-throughput social, behavioral, and neuropharmacological studiesSBC: CORNERSTONE RESEARCH GROUP INC Topic: 101
Project SummaryUltrasonic vocalizations (USVs) are known to reflect emotional processing, brain neurochemistry and brain function - key observations in animal model studies. Collecting and processing USV data is time-intensive, manual, and costly. Most importantly, it limits researchers’ ability to employ fully effective, and nuanced experimental designs, and is a barrier to entry for other rese ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health