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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AHTP-comet: development of an automated, high throughput comet assay system

    SBC: ENGINEERING RESOURCES GROUP INC            Topic: NIEHS

    PROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Advance Care Planning in the Dementias: Culturally-Tailored Caregiver Education for African Americans

    SBC: COLLINGE AND ASSOCIATES, INC.            Topic: N

    African Americans face significantly greater risk of Alzheimer s Disease and other dementias than white Americans but receive disproportionately less attention to dementia screening and supportresulting in a silent epidemic in this underserved populationAdvance Care Treatment PlanACT Planis a culturally tailored caregiver education program for African American dementia caregivers with decisional r ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Bioinformatic Tools for Interpretation of Glycan Array Data

    SBC: Z BIOTECH, LLC            Topic: 400

    Project SummaryAbstract There is an urgent need of bioinformatic tools for mining glycan array data in order to accurately and statistically study the interactions between cell surface glycans and glycan binding proteinsWe propose here to develop a software and hardware integrated system for the interpretation of glycan array dataThe problem with existing glycan array data mining tools is that the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Direct-read monitor for airborne viral pathogens

    SBC: AEROSOL DEVICES INC            Topic: NIAID

    Aerosolized pathogenssuch as Influenza virusescan spread rapidly and silently throughout a populationcausing severe outbreaks that can be difficult to controlEarly detection of these airborne pathogens is key to controlling outbreaksespecially among vulnerable populations such as in hospitalstreatment centers or nursing homesYet available methods are neither rapidnor portableCurrent methods rely h ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. ShRNA-Based Targeting of mAKAP? in Heart Failure

    SBC: CARDIAC RSK3 INHIBITORS, LLC            Topic: NHLBI

    Pathological cardiac remodeling constitutes a common pathway to heart failure in diseaseDespite current pharmacologic therapy and other advances that attenuate remodelingmortality due to heart failure remains highNewmore effective therapeutic options are desperately needed in an increasing patient population to improve both the survival and quality of life for patients with or susceptible to heart ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A Randomized Phase I Clinical Trial of HydroVax-YFV, a Novel Inativated Yellow Fever Vaccine

    SBC: NAJIT TECHNOLOGIES INC            Topic: NIAID

    Yellow fever virusYFVis a mosquito borne emerging re emerging hemorrhagic fever virus that causesmortality and is endemic in andgtcountriesThe current live attenuated YFV vaccine was developed inand has proven to be effective at saving millions of lives from this devastating diseaseNeverthelessthis is a live attenuated vaccine that is contraindicated in healthy people who have egg allergies as wel ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. SynthoPlate: Intravenous Hemostatic Nanotechnology to Mitigate Bleeding in Thrombocytopenia

    SBC: Haima Therapeutics LLC            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT The normal platelet count in human blood isLand these platelets are responsible for efficient hemostatic surveillance and bleeding mitigation in the bodyThrombocytopeniaTCPlow platelet countis a condition caused by a decrease in platelet productionincrease in platelet destruction or consumptionor increase in splenic sequestrationThe age adjusted prevalence of immune thromb ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Tools for Improved Translation of Novel Inhalable Therapeutics

    SBC: POWERSCOPE, INC            Topic: NHLBI

    Project Summary: With delineation of the pathogenesis of lung diseases, significant advances are being achieved in the pharmaceutical development of therapeutic interventions. New putative drugs are continually being identified; however, their initial availability is often extremely limited, particularly for biologically-based, macromolecule agents (e.g. proteins, genes, RNA, and antibodies). Tran ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. An Online Training Support System to Increase Community Clinic Use of an Evidence-Based Treatment for Opioid and Other Drug Addictions in Emerging Adults

    SBC: Sheidow Consulting, Inc.            Topic: NIDA

    PROJECT SUMMARY ABSTRACT The societal costs of drug addiction are astoundingover $billion annuallyexceeding costs for any other health problemThe opioid epidemicespeciallyis devastatingoverAmerican overdose deaths daily at a cost of $billion per yearEach yearmillion emerging adultsEAsagesuse illicit drugsinEAsand overmillion are in need of treatment for substance use disordersSUDEAs represent the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A multiscale computational tool to simulate the PK of orally-administered drugs in the human GI tract

    SBC: CFD RESEARCH CORPORATION            Topic: 400

    A multiscale computational tool to simulate the PK of orally administered drugs in the human GI tract Project Summary AbstractMost FDA approved drugs are administered orallydespite the complex process of oral drug absorption that is difficult to analyze experimentallyOral bioavailability is dependent on the interplay between multiple and simultaneous processes that are dependent on both the drug c ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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