You are here
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
SBC: SUN BIOPHARMA, INC. Topic: 300
Project Summary Pancreatitis is a significant public health problem accounting for over $ Billion of health care costs annually Approximately one third of patients with acute pancreatitis will go on to have recurrent pancreatitis Of those about will progress to chronic pancreatitis a painful disease with an increased risk of both diabetes and pancreatic cancer More than of people w ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Epigenetix Inc Topic: R41
PROJECT SUMMARY This proposal aims to develop a new small molecule drug to be advanced into human clinical trials for the treatment of cocaine addiction According to the National Institute on Drug Abuse illicit drug use cost the United States more than $ billion annually in expenses related to crime lost work productivity and health care Approximately million Americans aged or older ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
"Speed Bumps": A non-invasive quantitative test for early detection of neuropathy in the feetSBC: Neuro Devices, Inc. Topic: 101
ABSTRACT This STTR Phase I resubmission describes a small deceptively simple portable device called Speed Bumps that rapidly quantifies the sensation of flutter on the feet toes or fingers in micrometer m units Flutter frequency is to Hz which is below the approximate lower vibration range of to Hz This high sensitivity device is designed to differentiate the small variati ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: STONESTABLE, INC. Topic: NIAID
The goal of this Phase I STTR grant proposal is to stabilize live attenuated influenza vaccine LAIV using a temporary silica coating that is removed in vivo In so doing we will establish a broader technology to eliminate the cold chain required for transport of heat and cold labile vaccines Many vaccines are unstable under ambient environmental conditions Currently vaccines are either stabil ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
Simple, low cost assay for detection of HIV-1 antiretroviral resistance in resource-limited settingsSBC: Discidium Biosciences, LLC Topic: NIAID
Antiretroviral therapy has become a reality in resource limited settings thanks to entities such as PEFAR and the Global Fund However contrary to the therapeutic choice flexibility in developed countries all patients go on reverse transcriptase inhibitor RTI based first line regimens with more expensive protease and integrase inhibitor based regimens being reserved as second line therapy for ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Minnetronix Medical, Inc. Topic: 102
DESCRIPTION provided by applicant Directed Chemotherapy Delivery for Leptomeningeal Metastases PI Lad Shivanand and McCabe Aaron Project Summary Leptomeningeal Metastases LM is a condition in which cells from a primary solid or hematological tumor metastasize invade the subarachnoid space and spread throughout the cerebrospinal fluid CSF resulting in seeding of the leptomeninges along ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: H-CUBED Topic: NHLBI
DESCRIPTION provided by applicant Congenital diaphragmatic hernia CDH affects in newborns CDH is a disorder in which part of the diaphragm fails to form allowing abdominal organs to migrate into the chest resulting in lung hypoplasia underdevelopment in affected infants Although great strides have been made in the management of this disease significant morbidity and mortality p ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
Development of a novel platform to enhance intracellular bioavailability of antisense morpholino oligomersSBC: NAJIT TECHNOLOGIES INC Topic: NIAID
DESCRIPTION provided by applicant Peptide conjugated phosphorodiamidate morpholino oligomers PPMO are single stranded nucleic acid analogs able to modulate gene expression through steric blocking of complementary RNA PPMO are composed of two components an antisense morpholino oligomer cargo covalently conjugated to a cell penetrating delivery peptide PPMO are completely nuclease resistant ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
Novel Assay System and Analysis Algorithm in Detecting RNA Editing Events and Linked Splicing IsoformsSBC: Celetrix LLC Topic: NIDA
Abstract RNA editing is a process in which the genome encoded information is altered in RNA RNA editing is an efficient way to increase RNA complexity thereby fine tuning both gene function and dosage Adenosine to Inosine A to I editing is the most common type of RNA editing known in animals The cellular machinery recognizes inosine as guanosine so A to I editing of codons and splicing sign ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: NeurInsight, LLC Topic: 108
DESCRIPTION provided by applicant Surgical resection of brain neoplasms aims at maximizing long term survival by gross total resection of tumor tissue while preserving the patientandapos s functional status Task based functional MRI fMRI is increasingly used as an adjunct to intra operative electrocorticography for mapping eloquent cortex but suffers a significant failure rate due to funct ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health