Award Data

In this proposal, TiER1 Performance Solutions and Alion Science and Technology offer to develop A-TAUS (Automated Tool for Assessing Usability in Systems) to assist DHS engineers in improving usability without the burden of learning numerous disconnected tools. A primary goal of Phase I is to develop a proof-of-concept prototype that includes a research-based organizing framework for analyzing usa ...

In this proposal, TiER1 Performance Solutions and Alion Science and Technology offer to identify requirements and specifications, and implement a proof-of-concept prototype tool to support human factors evaluations. This prototype, called the Human Factors Evaluation Automated Tool (HFE-AT), will provide guidance, for non-human factors personnel, to address human factors-related aspects of the en ...

Future U.S. Information Systems will be subject to increased attacks. These attacks will come from both internal and external threats. As reflected by the budgets for combating these threats, external cyber threats are assumed to be more likely. By comparison, internal threats to cyber networks from U.S. personnel receive little attention; yet, the consequences can be even more devastating. Al ...

This Small Business Innovation Research (SBIR) Phase I project seeks to create a knowledge and training system that will reliably enable trainees and students to learn more material at a faster rate in any sector of society while, in the process: 1) advancing the scientific knowledge of the pedagogical underpinnings of learning acceleration (specifically through a better understanding of the indep ...

DESCRIPTION (provided by applicant): A Phase 1 SBIR program of pre-clinical development is proposed focusing on a novel rapid-acting insulin analog for the treatment of diabetes mellitus. Designated Insulin-Cl, our product is a derivative of insulin lispro (the active component of HumalogTM) containing a single chloro-substitution within the aromatic ring of a conserved phenylalanine in the B-chai ...

DESCRIPTION (provided by applicant): A Phase 1 SBIR program of pre-clinical development is proposed focusing on a novel long-acting insulin analog for the basal treatment of diabetes mellitus. Designated Insulin-ZN, our product is a derivative of human insulin containing novel zinc-binding sites at the periphery of the insulin hexamer. The non-classical zinc-binding sites are mediated by paired (i ...

DESCRIPTION (provided by applicant): Peripheral Vascular Disease (PVD) results from chronic loss of the oxygen supply to the lower limbs due to arterial blockage. Loss of oxygen to these tissues can result in pain, ulcers, infection and limb amputation in patients. PVD affects up to 12% of the population globally with increased risk in patients with diabetes, hypertension, advanced age and obesity ...

There are many commercially available flexible hoses for use in non-rigid coupling of hydraulic, air, and other piping systems. However, these systems are currently not designed for operating under severe hydrostatic and dynamic pressures experienced by Deep Submergence Systems in their extreme operating environments. The pipes that connect the DDS to the sub are exposed to the water and experien ...

We propose to implement a platform based on the .NET Micro Framework (MF) for mote-scale Wireless Sensor Networks (WSNs) and Active Tag Networks (ATNs). The resulting middleware would significantly simplify the development of applications on these systems, both by providing a hardware-independent, high-level, development environment and by providing standard implementations for essential services ...

In general, there are two ways an FSS Radome subjected to an HPM source can fail. The first is under a sustained continuous high average power signal where heating in lossy materials causes melting or burning. The second is under a very high peak power signal where arching or breakdown occurs within or around the FSS elements, essentially shorting them out. During the Phase I of this SBIR, nove ...